Results 51 to 60 of about 706,502 (262)
Animals, 2023 In this study, we analyzed the variation of reproductive efficiency, estimated as the deviation between the optimal and real parity number of females at each stage of the cow’s life, in 12,554 cows belonging to the Retinta Spanish cattle breed, using ...
José María Jiménez +5 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Journal of Dairy Science: Several studies have indicated that rumination could be used as a metric to monitor dairy cows' performance, condition, and health status. Along with applications in cow management, there may be scope to use rumination data in breeding programs ...
W. Lou +3 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Estimation of the Genetic Parameters for Test-Day Milk, in Teleorman Black Head Sheep
Scientific Papers Animal Science and Biotechnologies, 2023 The objective of this study was to determine the genetic parameters represented by heritability for test-day milk yield and the genetic correlation between test-days milk yield and the breeding value for Teleorman Black Head sheep. The genetic parameters
Rodica Stefania Pelmus +6 more
doaj
Random regression models for detection of gene by environment interaction [PDF]
Genetics Selection Evolution, 2007 Abstract Two random regression models, where the effect of a putative QTL was regressed on an environmental gradient, are described. The first model estimates the correlation between intercept and slope of the random regression, while the other model restricts this correlation to 1 or -1, which is expected under a bi-allelic QTL model.
Meuwissen Theo HE +2 more
openaire +4 more sources
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Revista Brasileira de Zootecnia, 2007 Foram utilizados 263.390 registros de produção de leite do dia do controle (PDC) de 32.448 primeiras lactações de vacas da raça Holandesa paridas no período de 1991 a 2001 para predizer valores genéticos usando diferentes modelos estatísticos e a ...
Cláudio Manoel Rodrigues de Melo +4 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Random regression models for genetic evaluation of clinical mastitis in dairy cattle
Animal, 2009 A genetic analysis of longitudinal binary clinical mastitis (CM) data recorded on about 90 000 first-lactation Swedish Holstein cows was carried out using linear random regression models (RRM).
E. Carlén +3 more
doaj +1 more source