Results 61 to 70 of about 707,184 (259)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Research on the Charging Load Calculation Method for Electric Vehicle Cluster

open access: yes南方能源建设
[Introduction] The widespread adoption of electric vehicles (EVs) enhances environmental sustainability during travel, yet it simultaneously elevates strain on the mains supply.
Lei YOU, Xiaoming JIN, Yun LIU
doaj   +1 more source

Estimators in simple random sampling: Searls approach [PDF]

open access: yesSongklanakarin Journal of Science and Technology (SJST), 2013
This paper investigates four new estimators in simple random sampling: biased sample mean, ratio estimator and two linear regression estimators, using known coefficients of variation of the study variable and auxiliary variable. The properties of the new
Jirawan Jitthavech   +1 more
doaj  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Analysis of decreasing squared-sum of Gram–Schmidt lengths for short lattice vectors

open access: yesJournal of Mathematical Cryptology, 2017
In 2015, Fukase and Kashiwabara proposed an efficient method to find a very short lattice vector. Their method has been applied to solve Darmstadt shortest vector problems of dimensions 134 to 150.
Yasuda Masaya   +4 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Simulation-Based Inference: Random Sampling vs. Random Assignment? What Instructors Should Know

open access: yesJournal of Statistics and Data Science Education
“Simulation-based inference” is often considered a pedagogical strategy for helping students develop inferential reasoning, for example, giving them a visual and concrete reference for deciding whether the observed statistic is unlikely to happen by ...
Beth Chance   +5 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Visual Tracking With Online Assessment and Improved Sampling Strategy

open access: yesIEEE Access, 2020
The kernelized correlation filter (KCF) is one of the most successful trackers in computer vision today. However its performance may be significantly degraded in a wide range of challenging conditions such as occlusion and out of view.
Meng Ding   +4 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy