Results 161 to 170 of about 2,891,219 (304)
Overrepresentation Bias Leads to Performance Overestimation in Blood-Brain Barrier Permeability Prediction Models: Characterization and Mitigation. [PDF]
J Chem Inf ModelFerri P, García-Gómez JM.
europepmc +1 more source
Integrals of random fuzzy sets
Random fuzzy sets, integrably bounded random fuzzy sets, Aumann-integral, Pettis-integral, Bochner-integral, dominated convergence theorems, strong law of large numbers, central limit theorems, Primary 60D05, Secondary 60F15,
Volker Krätschmer
core +1 more source
Adenosine triphosphate as a modulator of protein interactions and stability
FEBS Open Bio, EarlyView.ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
An introduction to random sets
, 2006 The study of random sets is a large and rapidly growing area with connections to many areas of mathematics and applications in widely varying disciplines, from economics and decision theory to biostatistics and image analysis.
Nguyen, Hung T
core
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
FEBS Open Bio, EarlyView.BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
Independent Sets of Random Trees and Sparse Random Graphs
Journal of Graph TheoryABSTRACTAn independent set of size in a finite undirected graph is a set of vertices of the graph, no two of which are connected by an edge. Let be the number of independent sets of size in the graph and let . In 1987, Alavi, Malde, Schwenk, and Erdős asked if the independent set sequence of a tree is unimodal (the sequence goes up and then down)
openaire +3 more sources
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Explainable artificial intelligence reveals divergent learning in pharmacophore-based hierarchical pooling graph neural networks. [PDF]
Sci RepUrrutia MJT, Mastropietro A, Bajorath J.
europepmc +1 more source
FEBS Open Bio, EarlyView.Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta +7 more
wiley +1 more source