Results 91 to 100 of about 6,730,982 (293)

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Estimating the intercept in an orthogonally blocked experiment when the block effects are random. [PDF]

: For an orthogonally blocked experiment, Khuri (1992) has shown that the ordinary least squares estimator and the generalized least squares estimator of the factor effects in a response surface model with random block effects coincide.
Goos, Peter, Vandebroek, Martina
core  

Modelling Geometric Deviations in Additive Manufacturing of a Cylindrical Surface

Journal of Machine Engineering
This work presents, in a first part, a state of the art on geometric deviation modelling in additive manufacturing. It then proposes a geometric deviation modelling methodology based on part discretization, considering the systematic and random ...
Ikram Kabbouri, Anass El-qemary, Mouhssine Chahbouni, Said Boutahari   +3 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Coupled nonlinear surface reactions in random walk particle tracking

Random walk particle tracking (RWPT) methods employ a Lagrangian discretization of transported scalars into point particles to numerically solve the advection–dispersion equation.
Aquino, Tomás
core   +1 more source

Touching random surfaces and Liouville gravity [PDF]

Physical Review D, 1995
Large $N$ matrix models modified by terms of the form $ g(\TrΦ^n)^2$ generate random surfaces which touch at isolated points. Matrix model results indicate that, as $g$ is increased to a special value $g_t$, the string susceptibility exponent suddenly jumps from its conventional value $γ$ to ${γ\overγ-1}$.
openaire   +3 more sources

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Random vibration study of cold rolling mill excited by different morphology of strip surface

Advances in Mechanical Engineering
In order to investigate the random vibration characteristics of a cold rolling mill under the excitation of different morphologies on the strip surface and to study the spatial distribution of vibration amplitude inside the key components of the cold ...
Sun Weiquan, Yan Xiaoqiang, Wang Shen, Xuan Lijian, Yun Weijing, Chen Yuchen   +5 more
doaj   +1 more source

Evaluation the Simple Spatial Interpolation Method to Identifying The Groundwater in Erbil Governorate

Zanco Journal of Humanity Sciences, 2018
In this research used Simple Kriging method as one of Geostatistics interpolation methods on the measured value of the specific part in Erbil. Geostatistics is a set of (tools and models) that are developed for statistical analysis of any continuous data
Paree khan Aabdulla Omer
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source