Results 251 to 260 of about 2,921,645 (302)

Harnessing Large‐Scale Multi‐Omics Data for Risk Prediction and Deep Phenotyping of Valvular Heart Diseases in the General Population

Advanced Science, EarlyView.
Large‐scale UK Biobank analyses identify clinical and proteomic signatures for early prediction of valvular heart disease and its subtypes. Proteins add predictive value for VHD, AVS, and MVR, with outcome‐specific compact panels showing translational potential. Multi‐layer evidence highlights matrix remodeling, protease regulation, immune inflammation,
Zhihao Jiang, Yang Liu, Mingyu Song, Ning Chen, Canqing Yu, Jun Lv, Eric Yuk Fai Wan, Lu Qi, Liming Li, Dianjianyi Sun, Bang Zheng   +10 more
wiley   +1 more source

Explainable Machine Learning for Risk Prediction of Reduced Quality of Life in Hypertension. [PDF]

Vasc Health Risk Manag
Andala S, Iqhrammullah M, Agusri A, De Liyis BG, Rampengan DDCH, Rampengan SH, Fahdhienie F, Habiburrahman M.   +7 more
europepmc   +1 more source

High Tree Species Diversity Promotes Thermal Enhancement Response of Microbial Carbon Use Efficiency

Advanced Science, EarlyView.
ABSTRACT Predicting soil carbon dynamics under warming is constrained by limited understanding of microbial thermal adaptation, particularly whether microbial carbon use efficiency (CUE) can adapt to warming and how plant diversity modulates this response. Using soils from a natural tree species diversity gradient in a subtropical forest, we combined a
Pengpeng Duan, Changqing Ye, Xinyi Yang, Chaoqun Wang, Wolfgang Wanek, Jian‐sheng Ye, Hongzhao Yuan, Hu Du, Kongcao Xiao, Xunyang He, Kelin Wang, Dejun Li   +11 more
wiley   +1 more source

Modelling forest carbon stocks on the Canary Islands. [PDF]

Carbon Balance Manag
Otto R, García-Alvarado JJ, Rocafull E, Sierra Cornejo N, Irl SDH, Rodríguez Arvelo F, Ruíz-Peinado R, Fernández-Palacios JM, de Nascimento L.   +8 more
europepmc   +1 more source

Calcineurin‐Dependent Stress Adaptation Enables Caspofungin Heteroresistance Leading to Stable Resistance in Candida Glabrata

Advanced Science, EarlyView.
Caspofungin heteroresistance is prevalent in clinical Candida glabrata isolates and depends on calcineurin‐mediated stress adaptation. This transient phenotype serves as a reservoir for resistance evolution, enabling the emergence of stable resistant descendants under prolonged drug pressure.
Yanyu Su, Yi Li, Meng Xiao, Dan Guo, David S. Perlin, Erika Shor, Yingchun Xu, Yingxing Li   +7 more
wiley   +1 more source

Exploring data-driven algorithms to identify Lyme disease cases in electronic health records. [PDF]

PLoS One
Linz AM, Scotty E, Meece JK, Nawrocki CC, Kugeler KJ, Hook SA, Hinckley AF, Schotthoefer AM.   +7 more
europepmc   +1 more source

Machine Learning and Metabolomics to Characterize Warburg-Like Metabolic Subtypes in Human Retinal Endothelial Cells Exposed to Risk Factors Associated With Proliferative Diabetic Retinopathy. [PDF]

Transl Vis Sci Technol
Sbei O, Eltanani S, Ibrahim S, Yumnamcha T, Srinivas SP, Ibrahim AS.   +5 more
europepmc   +1 more source

Development and Explainable Machine Learning Validation of a Novel Sleep Disturbance Ratio for Obstructive Sleep Apnea Severity Assessment. [PDF]

Diagnostics (Basel)
Kabak M, Irmak H, Kılıç AR, Çil B.
europepmc   +1 more source

Clinically interpretable prediction models of stroke functional outcomes: A national cohort study of adults in inpatient rehabilitation facilities in the US. [PDF]

Arch Phys Med Rehabil
Cogan AM, Wen Y, Nie D, Ye D, Winstein CJ, Schweighofer N.   +5 more
europepmc   +1 more source

Family context, directed and random exploration profiles, and child socioemotional functioning. [PDF]

Dev Psychopathol
Li Z, Li Y, Davies PT, Sturge-Apple ML.
europepmc   +1 more source