Results 41 to 50 of about 246,128 (313)

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

A new generation tree for permutations, preserving the number of fixed points [PDF]

open access: yesDiscrete Mathematics & Theoretical Computer Science, 2014
We describe a new uniform generation tree for permutations with the specific property that, for most permutations, all of their descendants in the generation tree have the same number of fixed points.
Philippe Duchon, Romaric Duvignau
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Limits of random trees [PDF]

open access: yesActa Mathematica Hungarica, 2013
Local convergence of bounded degree graphs was introduced by Benjamini and Schramm. This result was extended further by Lyons to bounded average degree graphs. In this paper, we study the convergence of a random tree sequence where the probability of a given tree is proportional to $\prod_{v_i\in V(T)}d(v_i)!$.
openaire   +2 more sources

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Rapidly exploring Random Tree* with a sampling method based on Sukharev grids and convex vertices of safety hulls of obstacles

open access: yesInternational Journal of Advanced Robotic Systems, 2019
The path planning for an Unmanned Aerial Vehicles ensures that a dynamically feasible and collision-free path is planned between a start and an end point within a navigation environment.
Luiz GDO Véras   +2 more
doaj   +1 more source

DPRF: A Differential Privacy Protection Random Forest

open access: yesIEEE Access, 2019
Providing privacy protection for classification algorithms has become a research hotspot in current data mining. In this paper, differential privacy is applied to the random forest classification algorithm, and a random forest algorithm based on ...
Jun Hou   +5 more
doaj   +1 more source

Improved Bidirectional RRT* Algorithm for Robot Path Planning

open access: yesSensors, 2023
In order to address the shortcomings of the traditional bidirectional RRT* algorithm, such as its high degree of randomness, low search efficiency, and the many inflection points in the planned path, we institute improvements in the following directions.
Peng Xin   +5 more
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

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