Results 41 to 50 of about 943,517 (257)
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
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Вестник Самарского университета: Аэрокосмическая техника, технологии и машиностроениеAn experimental method has been developed that makes it possible to obtain the kinematic parameters of a particle moving in an air stream, while colliding with the surface of an airfield.
E. V. Neskoromnyy +2 more
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Probabilistic Computational Model for Correlated Wind Farms Using Copula Theory
IEEE Access, 2018 This paper proposed a probabilistic load flow analysis of correlated wind farms based on Copula theory. This method addresses the linear and non-linear dependence between random variables more efficiently and accurately than other methods.
Li Bin +5 more
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Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Random semilinear system of differential equations with impulses
Fixed Point Theory and Applications, 2017 In this paper, we study the existence of solutions for systems of random semilinear impulsive differential equations. The existence results are established by means of a new version of Perov’s, a nonlinear alternative of Leray-Schauder’s fixed point ...
A Baliki, JJ Nieto, A Ouahab, ML Sinacer
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, 2017 We introduce a new `geometric realization' of an (abstract) simplicial complex, inspired by probability theory. This space (and its completion) is a metric space, which has the right (weak) homotopy type, and which can be compared with the usual geometric realization through a natural map, which has probabilistic meaning : it associates to a random ...
openaire +3 more sources
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
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PROBABILISTIC FLOW MODEL OF FREIGHT ORDERING WITH CONSIDERATION OF REGULARITIES OF THEIR RECEPTION [PDF]
Avtomobilʹnyj Transport (Harʹkov), 2014 An analytical model for calculating the probability of freightage obtaining by concrete carrier is proposed. The model takes into account the freightage waiting time, the parameters of a single freight flow and freight structure parameters.
P. Gorbachov, А. Makarychev, N. Kuzlo
doaj
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
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FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source