Results 91 to 100 of about 702,734 (359)

Comparison of the collagen haemostat Sangustop(R) versus a carrier-bound fibrin sealant during liver resection; ESSCALIVER-study [PDF]

, 2010
Background: Haemostasis in liver surgery remains a challenge despite improved resection techniques. Oozing from blood vessels too small to be ligated necessitate a treatment with haemostats in order to prevent complications attributed to bleeding.
A Frilling, C Broelsch, Christian Moench, G Piaggio, Godehard Hoexter, Hanns-Peter Knaebel, I Takacs, J Kruger, M Schwartz, RG Newcombe, S Siemer, TW Kraus, Valentin Hermanutz, WC Chapman, WO Bechstein, Wolf O Bechstein   +15 more
core   +3 more sources

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

Molecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Elin Borgen, Cecilie Bendigtsen Schirmer, Bjørnar Gilje, Øystein Garred, Jon Lømo, Marius Stensland, Oddmund Nordgård, Ragnhild Sørum Falk, Randi R. Mathiesen, Hege G. Russnes, Jon Amund Kyte, Bjørn Naume   +13 more
wiley   +1 more source

Update to: Assessing the efficacy of male Wolbachia-infected mosquito deployments to reduce dengue incidence in Singapore

Trials
Background This trial is a parallel, two-arm, non-blinded cluster randomised controlled trial that is under way in Singapore, with the aim of measuring the efficacy of male Wolbachia-infected Aedes aegypti deployments in reducing dengue incidence in an ...
Jue Tao Lim, Diyar Mailepessov, Chee-Seng Chong, Chia-Chen Chang, Borame Dickens, Yee Ling Lai, Lu Deng, Caleb Lee, Li Yun Tan, Grace Chain, Soon Hoe Ho, Muhammad Faizal Zulkifli, Jonathan Liew, Kathryn Vasquez, Vernon Lee, Judith Chui Ching Wong, Shuzhen Sim, Cheong Huat Tan, Lee Ching Ng   +18 more
doaj   +1 more source

Open versus laparoscopic left lateral hepatic sectionectomy within an enhanced recovery ERAS® programme (ORANGE II – Trial): study protocol for a randomised controlled trial

Trials, 2012
Background The use of lLaparoscopic liver resection in terms of time to functional recovery, length of hospital stay (LOS), long-term abdominal wall hernias, costs and quality of life (QOL) has never been studied in a randomised controlled trial ...
van Dam Ronald M, Wong-Lun-Hing Edgar M, van Breukelen Gerard JP, Stoot Jan HMB, van der Vorst Joost R, Bemelmans Marc HA, Damink Steven WM, Lassen Kristoffer, Dejong Cornelis HC   +8 more
doaj   +1 more source

A randomised controlled trial to compare the clinical and cost-effectiveness of prism glasses, visual search training and standard care in patients with hemianopia following stroke: a protocol [PDF]

, 2014
INTRODUCTION: Homonymous hemianopia is a common and disabling visual problem after stroke. Currently, prism glasses and visual scanning training are proposed to improve it.
Barrett, Black, Bouwmeester, Bowers, Department of Health, Dombovy, Giorgi, Gray, Jones, Jongbloed, Kaplan, Kerkhoff, Lancaster, Machin, Pambakian, Peli, Pollock, Pollock, Pollock, Ramrattan, Riggs, Rossi, Rowe, Rowe, Rowe, Royal College of Physicians Intercollegiate Stroke Working Party, Schofield   +26 more
core   +2 more sources

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

Molecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić, Florian Lüke, Steffi Treitschke, Andrea Coluccio, Martin Hoffmann, Giancarlo Feliciello, Adithi Ravikumar Varadarajan, Xin Lu, Kathrin Weidele, Catherine Botteron, Silvia Materna–Reichelt, Felix Keil, Katja Evert, Florian Weber, Thomas Schamberger, Michael Althammer, Jirka Grosse, Dirk Hellwig, Christian Schulz, Stephan Seitz, Peter Ugocsai, Anke Schlenska‐Lange, Roman Mayr, Ulrich Kaiser, Wolfgang Dietmaier, Bernhard Polzer, Jens Warfsmann, Kamran Honarnejad, Tobias Pukrop, Daniel Heudobler, Christoph A. Klein, Christian Werno   +31 more
wiley   +1 more source

Singing classes for chronic obstructive pulmonary disease: a randomized controlled trial

BMC Pulmonary Medicine, 2012
Background There is some evidence that singing lessons may be of benefit to patients with chronic obstructive pulmonary disease (COPD). It is not clear how much of this benefit is specific to singing and how much relates to the classes being a group ...
Lord Victoria M, Hume Victoria J, Kelly Julia L, Cave Phoene, Silver Judith, Waldman Maya, White Chris, Smith Cayley, Tanner Rebecca, Sanchez Melissa, Man William D-C, Polkey Michael I, Hopkinson Nicholas S   +12 more
doaj   +1 more source

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

Molecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld, Stefan Kühberger, Ricarda Graf, Christine Beichler, Markus Braun, Nadia Dandachi, Ellen Heitzer, Gerald W. Prager   +7 more
wiley   +1 more source

Effect of 12-week shen-based qigong exercise on the residual symptoms of schizophrenia: Study protocol for a single-centre randomised controlled trial

Contemporary Clinical Trials Communications, 2023
Introduction: Negative symptoms and cognitive impairment are common residual symptoms of schizophrenia that seriously affect the quality of life and social function of patients.
Anbei Lian, Qing Fan, Wenzheng Wang, Qinxin Liu, Jiacheng Shi, Min Zhuang, Yujie Li, Xiaodan Liu   +7 more
doaj  

Establishing cost-effectiveness of genetic targeting of cancer therapies\ud [PDF]

, 2008
The clinical benefit of a new genomic instrument, the 70-gene signature\ud for breast cancer patients, is being evaluated in a randomised clinical\ud trial.
Harten, W.H. van, Joore, M.A., Retèl, Valesca P., Rutgers, E.J.Th.   +3 more
core   +2 more sources