Results 121 to 130 of about 760,498 (359)

Development and delivery of a physiotherapist-led exercise intervention in a randomised controlled trial for subacromial impingement syndrome (the SUPPORT trial) [PDF]

, 2017
Purpose This paper describes the development, content and delivery of a physiotherapist- led individualised, supervised and progressed exercise programme for use in a factorial randomised controlled trial testing treatments for subacromial impingement ...
Foster, NE, Jackson, S, Roddy, E, Shufflebotham, J, Stevenson, K   +4 more
core   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Meropenem vs standard of care for treatment of late onset sepsis in children of less than 90 days of age: study protocol for a randomised controlled trial

Trials, 2011
Background Late onset neonatal sepsis (LOS) with the mortality of 17 to 27% is still a serious disease. Meropenem is an antibiotic with wide antibacterial coverage.
de Cabre Vincent, Esposito Susanna, Standing Joseph, Metsvaht Tuuli, Heath Paul T, Trafojer Ursula MT, Lutsar Irja, Oeser Clarissa, Aboulker Jean-Pierre   +8 more
doaj   +1 more source

Effects of antenatal multiple micronutrient supplementation on children's weight and size at 2 years of age in Nepal: follow-up of a double-blind randomised controlled trial [PDF]

, 2008
Anjana Vaidya, Naomi Saville, Bhim P. Shrestha, Anthony Costello, Dharma Manandhar, David Osrin   +5 more
openalex   +1 more source

Timing and volume of fluid administration for patients with bleeding [PDF]

, 2003
Original article can be found at: http://www3.interscience.wiley.com Copyright John Wiley & Sons. ‘This review is published as a Cochrane Review in the Cochrane Database of Systematic Reviews 2003, Issue 3.
Bunn, Frances, Kwan, I., Roberts, I.
core   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

A falls prevention programme to improve quality of life, physical function and falls efficacy in older people receiving home help services: study protocol for a randomised controlled trial [PDF]

, 2017
BACKGROUND: Falls and fall-related injuries in older adults are associated with great burdens, both for the individuals, the health care system and the society. Previous research has shown evidence for the efficiency of exercise as falls prevention.
A Bandura, A Dadgari, A Saletti, A Vuillemin, AC Scheffer, AF Ambrose, AJ Campbell, AP Vivanti, Astrid Bergland, B Meinow, B Senn, B Vellas, C Luthy, C Meyer, C Sherrington, C-H Chou, CJ Jones, CMA Marques-Vieira, D Altman, Dawn A. Skelton, DM Landers, DM Peters, E McAuley, E McAuley, E McAuley, E McInnes, ER Vieira, ET Petridou, F El-Khoury, FB Gillison, G Salkeld, GA Kelley, HC Kraemer, I Vikman, JH Loge, K Christensen, K Delbaere, K Frändin, K Hawkins, K Haywood, KF Schulz, KF Schulz, KJ Preacher, KO Berg, L Yardley, LF Hektoen, LS Acree, LZ Rubenstein, M Bonnefoy, M Herdman, M Janssen, M Lawton, M Markle-Reid, M Ory, Maria Bjerk, MC Robertson, N Vries De, PC Fletcher, PC Fletcher, R Brooks, R Elkan, R Forkan, S Heydarnejad, S Hollis, S Michie, S Vaapio, SE Lamb, SE Lamb, SM White, SS Vaapio, T Brovold, The EuroQol Group, The WHOQOL Group, Therese Brovold, TN Tombaugh, Y Guigoz, Y Hellström, Y Netz   +77 more
core   +1 more source

Randomised controlled trials are important

BMJ, 1999
EDITOR—Cranberg's arguments against controlled trials and in favour of historical controls supported by data on matching for known risk factors are seriously flawed.1 There are at least four fallacies. Firstly, the matching procedures …
openaire   +3 more sources

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Efficacy of memantine in the treatment of fibromyalgia: A double-blind, randomised, controlled trial with 6-month follow-up [PDF]

, 2014
Bárbara Oliván‐Blázquez, Paola Herrera‐Mercadal, Marta Puebla‐Guedea, Mari‐Cruz Pérez‐Yus, Eva Andrés, Nicolás Fayed, Yolanda López del Hoyo, Rosa Magallón-Botaya, Miquel Roca, Javier Garcı́a-Campayo   +9 more
openalex   +1 more source