Intra-articular hyaluronan injections in the treatment of osteoarthritis of the knee: a randomised, double blind, placebo controlled multicentre trial. Hyaluronan Multicentre Trial Group. [PDF]
Stefan Lohmander+10 more
openalex +1 more source
Histone Deacetylase 6 Brain PET in Amyotrophic Lateral Sclerosis‐Frontotemporal Spectrum Disorder
ABSTRACT Objective [18F]EKZ‐001 is a positron emission tomography (PET) tracer targeting histone deacetylase 6 (HDAC6), an enzyme responsible for intracellular transport and clearance of misfolded proteins. HDAC6 modulation is a promising treatment strategy in neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS).
Greet Vanderlinden+15 more
wiley +1 more source
Sonolysis during carotid endarterectomy: randomised controlled trial.
Školoudík D+8 more
europepmc +2 more sources
Intraoperative methadone for postoperative pain in adult patients undergoing tonsillectomy-a randomised controlled trial. [PDF]
Bøndergaard M+8 more
europepmc +1 more source
Evaluation of a stroke family care worker: results of a randomised controlled trial [PDF]
Michelle F. Dennis+4 more
openalex +1 more source
Glycosylation Gene Signatures as Prognostic Biomarkers in Glioblastoma
ABSTRACT Objective Glioblastoma (GBM) is an aggressive brain tumor characterized by significant heterogeneity. This study investigates the role of glycosylation‐related genes in GBM subtyping, prognosis, and response to therapy. Methods We analyzed mRNA expression data and clinical information from The Cancer Genome Atlas (TCGA) and Gene Expression ...
Tong Zhao+4 more
wiley +1 more source
A comparison of frequentist and Bayesian approaches to the Personalised Randomised Controlled Trial (PRACTical)-design and analysis considerations. [PDF]
Jackson H+7 more
europepmc +1 more source
Randomised controlled trial of azithromycin in smokers with asthma [PDF]
Anderson, K.+13 more
core +2 more sources
Randomised controlled trial of laparoscopic versus open repair of inguinal hernia: early results [PDF]
K. Lawrence+7 more
openalex +1 more source
Myostatin Levels in SMA Following Disease‐Modifying Treatments: A Multi‐Center Study
ABSTRACT Objective This study investigated myostatin levels in SMA patients receiving disease‐modifying therapies (DMTs) to understand their relationship with treatment duration and functional status. Methods Our study includes both cross‐sectional and longitudinal analyses of myostatin levels in treated SMA patients.
Fiorella Piemonte+23 more
wiley +1 more source