Factors for Rituximab Refractoriness in AQP4‐IgG+ NMOSD: A Cohort Study
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a severe autoimmune condition of the central nervous system (CNS), often associated with aquaporin‐4 antibodies (AQP4‐IgG). Rituximab, a CD20+ B‐cell depleting monoclonal antibody, is widely used as first‐line therapy.
Mariano Marrodan+8 more
wiley +1 more source
Optimising access to vocational rehabilitation through multiple sclerosis charities: Protocol for a feasibility randomised controlled trial. [PDF]
De Dios Pérez B+5 more
europepmc +1 more source
Preventing injuries in children: cluster randomised controlled trial in primary care [PDF]
openalex +1 more source
Randomised controlled trials: sampling. [PDF]
openaire +3 more sources
ABSTRACT Introduction The kappa‐free light chain (κ‐FLC) index is known to be highly sensitive and specific for diagnosing multiple sclerosis (MS), while little is understood about lambda (λ)‐FLC. This study assessed the κ‐FLC and λ‐FLC indices in autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy.
Michael Levraut+11 more
wiley +1 more source
Handheld fans for dyspnoea in respiratory failure: randomised controlled trial. [PDF]
Yue D+5 more
europepmc +1 more source
Human albumin administration in critically ill patients: systematic review of randomised controlled trials Why albumin may not work [PDF]
openalex +1 more source
ABSTRACT Objective To compare the effectiveness of high‐efficacy treatments (HET) and low‐efficacy treatments (LET) in NMOSD patients with anti‐aquaporin‐4 antibodies (AQP4‐ab). Methods In this multi‐center study, we analyzed 183 AQP4‐ab seropositive NMOSD patients who received immunosuppressive treatments (IST).
Xiang Li+10 more
wiley +1 more source
Development and Testing of an Out-of-School Hours Care Professional Development Program: A Pilot Cluster Randomised Controlled Trial. [PDF]
Woods AJ+11 more
europepmc +1 more source
Eradication of Helicobacter pylori in functional dyspepsia: randomised double blind placebo controlled trial with 12 months' follow up [PDF]
Nicholas J. Talley+4 more
openalex +1 more source