Results 281 to 290 of about 760,498 (359)
Identifying Continence OptioNs after Stroke (ICONS): an evidence synthesis, case study and exploratory cluster randomised controlled trial of the introduction of a systematic voiding programme for patients with urinary incontinence after stroke in secondary care
, 2015 Lois Thomas, Beverley French, Chris Sutton, Denise Forshaw, Michael J Leathley, Christopher R Burton, Brenda Roe, Francine Cheater, Jo Booth, Elaine McColl, Bernie Carter, Andrew Walker, Katie Brittain, Gemma Whiteley, Helen Rodgers, James Barrett, Caroline Watkins, on behalf of the ICONS project team and the ICONS patient, public and carer involvement groups +17 moreopenalex +2 more sourcesUnraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective
Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou +10 morewiley +1 more sourceEffect of simvastatin on postoperative complications in patients undergoing one-lung ventilation during surgery: the Prevention HARP-2 randomised controlled trial
Adam Glass, Cecilia O’Kane, Akesh Dhrampal, Eustace Fontaine, James Ryan, Mahmoud Loubani, Sridhar Rathinam, Babu Naidu, Ingeborg Welters, Jonathan A. Silversides, Bilal Alkhaffar, Jeremy D. Hayden, Ewen A. Griffiths, David Chan, Annmarie Doran, Sorcha Toase, Christina Campbell, Ashley Agus, Gavin D. Perkins, Daniel F. McAuley, Murali Shyamsundar +20 moreopenalex +1 more sourceTraumatic Microhemorrhages Are Not Synonymous With Axonal Injury
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT
Diffuse axonal injury (DAI) is caused by acceleration‐deceleration forces during trauma that shear white matter tracts. Susceptibility‐weighted MRI (SWI) identifies microbleeds that are considered the radiologic hallmark of DAI and are used in clinical prognostication.Karinn Sytsma, Rhonda Mittenzwei, Heather Maioli, Amanda Kirkland, C. Dirk Keene, Ramon Diaz‐Arrastia, Christine Mac Donald, Chiara Maffei, Brian L. Edlow, Amber L. Nolan +9 morewiley +1 more sourceProcess evaluation for the STAMINA randomised controlled trial: A protocol. [PDF]
PLoS OneIbeggazene S, Reale S, Scope A, Price G, Sutton E, Bourke L, Collinson M, Stokes J, Steed L, Rosario D, Farrin AJ, Taylor SJC. +11 moreeuropepmc +1 more sourceClinically Relevant Outcome Measures in Women With Adrenoleukodystrophy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT
Adrenoleukodystrophy is a rare inherited peroxisomal disease caused by pathogenic variants in the ABCD1 gene located on the X chromosome. Although the most severe central nervous system and adrenal complications typically affect only men with adrenoleukodystrophy, the majority of women develop myeloneuropathy symptoms in adulthood.Chenwei Yan, Elizabeth I. Pierpont, Amena S. Fine, Reena V. Kartha +3 morewiley +1 more sourceRemote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective
Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether +20 morewiley +1 more source