Results 101 to 110 of about 1,461,213 (320)
Molecular Oncology, EarlyView.Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser +11 more
wiley +1 more source
OENO One, 1992 Des essais comparatifs entre clones traités par thermothérapie et clones témoins de quatre variétés: Chenin B., Carignan N., Cinsaut N., Grenache N. ont été conduits selon un dispositif de randomisation totale. Les analyses statistiques réalisées pendant
Serge Grenan, Claude Valat
doaj +1 more source
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
Properly Quantized History Dependent Parrondo Games, Markov Processes, and Multiplexing Circuits [PDF]
, 2009 In the context of quantum information theory, "quantization" of various mathematical and computational constructions is said to occur upon the replacement, at various points in the construction, of the classical randomization notion of probability ...
Bleiler, Steven A., Khan, Faisal Shah
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Random Walks in a Random Environment
The Annals of Probability, 1975 Let $\{\alpha_n\}$ be a sequence of independent, identically distributed random variables with $0 \leqq \alpha_n \leqq 1$ for all $n$. The random walk in a random environment on the integers is the sequence $\{X_n\}$ where $X_0 = 0$ and inductively $X_{n+1} = X_n + 1, (X_n - 1)$, with probability $\alpha_{X_n}, (1 - \alpha_{X_n})$.
openaire +3 more sources
Random walks on random trees [PDF]
Journal of the Australian Mathematical Society, 1973 Let T denote one of the nn−2 trees with n labelled nodes that is rooted at a given node x (see [6] or [8] as a general reference on trees). If i and j are any two nodes of T, we write i ∼ j if they are joined by an edge in T. We want to consider random walks on T; we assume that when we are at a node i of degree d the probability that we proceed to ...
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Molecular Oncology, EarlyView.Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla +5 more
wiley +1 more source
Bridging case-control studies and randomized trials
Current Controlled Trials in Cardiovascular Medicine, 2001 Randomized trials and observational studies, such as case-control studies, are often seen as opposing approaches. However, in many instances results obtained by different designs may complement each other.
Rosendaal Frits R
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Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source
Using Randomization in Development Economics Research: A Toolkit [PDF]
This paper is a practical guide (a toolkit) for researchers, students and practitioners wishing to introduce randomization as part of a research design in the field.
Esther Duflo +2 more
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