Results 21 to 30 of about 19,442,486 (302)

Integrated in silico Analyses of Regulatory and Metabolic Networks of Synechococcus sp. PCC 7002 Reveal Relationships between Gene Centrality and Essentiality

open access: yesLife, 2015
Cyanobacteria dynamically relay environmental inputs to intracellular adaptations through a coordinated adjustment of photosynthetic efficiency and carbon processing rates.
Hyun-Seob Song   +5 more
doaj   +1 more source

The Holdout Randomization Test for Feature Selection in Black Box Models

open access: yesJournal of Computational And Graphical Statistics, 2018
We propose the holdout randomization test (HRT), an approach to feature selection using black box predictive models. The HRT is a specialized version of the conditional randomization test (CRT) that uses data splitting for feasible computation.
Wesley Tansey   +4 more
semanticscholar   +1 more source

Randomization Tests that Condition on Non-Categorical Covariate Balance

open access: yesJournal of Causal Inference, 2019
A benefit of randomized experiments is that covariate distributions of treatment and control groups are balanced on average, resulting in simple unbiased estimators for treatment effects.
Branson Zach, Miratrix Luke W.
doaj   +1 more source

Cautionary note on calculating standardized effect size (SES) in randomization test

open access: yesCommunity Ecology, 2018
In community ecology, randomization tests with problem specific test statistics (e.g., nestedness, functional diversity, etc.) are often applied. Researchers in such studies may want not only to detect the significant departure from randomness, but also ...
Z. Botta‐Dukát
semanticscholar   +1 more source

Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression

open access: yesInternational Journal of Epidemiology, 2015
Background: The number of Mendelian randomization analyses including large numbers of genetic variants is rapidly increasing. This is due to the proliferation of genome-wide association studies, and the desire to obtain more precise estimates of causal ...
J. Bowden, G. Davey Smith, S. Burgess
semanticscholar   +1 more source

Randomization test of mean is compuationally inaccessible when the number of groups exceeds two [PDF]

open access: yesTutorials in Quantitative Methods for Psychology, 2011
With the advent of fast computers, the randomization test of mean (also called the permutation test) received some attention in the recent years. Here we show that the randomization test is possible only for two-group design; comparing three groups ...
Denis Cousineau
doaj  

A simulation study for comparing testing statistics in response-adaptive randomization

open access: yesBMC Medical Research Methodology, 2010
Background Response-adaptive randomizations are able to assign more patients in a comparative clinical trial to the tentatively better treatment. However, due to the adaptation in patient allocation, the samples to be compared are no longer independent ...
Lee J Jack, Gu Xuemin
doaj   +1 more source

Interpreting findings from Mendelian randomization using the MR-Egger method

open access: yesEuropean Journal of Epidemiology, 2017
Mendelian randomization-Egger (MR-Egger) is an analysis method for Mendelian randomization using summarized genetic data. MR-Egger consists of three parts: (1) a test for directional pleiotropy, (2) a test for a causal effect, and (3) an estimate of the ...
S. Burgess, S. Thompson
semanticscholar   +1 more source

Accurate Discrimination of Mold-Damaged Citri Reticulatae Pericarpium Using Partial Least-Squares Discriminant Analysis and Selected Wavelengths

open access: yesFoods
Unscrupulous merchants sell the mold-damaged Citri Reticulatae Pericarpium (CRP) after removing the mold. In this study, an accurate and non-destructive strategy was developed for the discrimination of mold-damaged CRPs using portable near-infrared (NIR)
Huizhen Tan   +5 more
doaj   +1 more source

Causal effects of gut microbiota on appendicitis: a two-sample Mendelian randomization study

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
BackgroundPrevious research has posited a potential correlation between the gut microbiota and the onset of appendicitis; however, the precise causal connection between appendicitis and the gut microbiota remains an unresolved and contentious issue ...
Zehui Wang   +7 more
doaj   +1 more source

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