Results 61 to 70 of about 10,207,361 (300)

A Heuristic for Graph Coloring Based on the Ising Model

Mathematics
We propose a dynamic extension of the Petford–Welsh coloring algorithm that estimates the chromatic number of a graph without requiring k as an input.
Omkar Bihani, Janez Žerovnik
doaj   +1 more source

Balance algorithm for cluster randomized trials

BMC Medical Research Methodology, 2008
Background Within cluster randomized trials no algorithms exist to generate a full enumeration of a block randomization, balancing for covariates across treatment arms.
Hood Kerenza, Carter Ben R
doaj   +1 more source

Monte-Carlo randomized algorithm: Empirical analysis on real-world information systems

International Convention on Information and Communication Technology, Electronics and Microelectronics, 2012
Determination of development priority of information system subsystems is a problem that warrants resolution during information system development. It has been proven, previously, that this problem of information system development order is in fact NP ...
R. Kudelić, D. Oreški, Mario Konecki
semanticscholar   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

An accelerated randomized Kaczmarz algorithm [PDF]

Mathematics of Computation, 2015
The randomized Kaczmarz ( R K \rm {RK} )
Ji Liu 0002, Stephen J. Wright 0001
openaire   +3 more sources

General Position Subset Selection in Line Arrangements

Algorithms
Given a set of n points in a plane, the General Position Subset Selection problem is that of finding a maximum-size subset of points in general position, i.e., with no three points collinear.
Adrian Dumitrescu
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

CluM: A Clustering–Cum–Markov model for resource prediction in a data center

International Journal of Applied Mathematics and Computer Science
High-end data centers are required to process the user requests and provide them with a better quality of service. The prominent issues in building a sustainable data center are reduced carbon footprint, dynamic capacity planning to reduce resource ...
Govindarajan Madhupriya, Selvaraj Mercy Shalinie, Ravi Nagarathna   +2 more
doaj   +1 more source