Encouraging GPs to undertake screening and a brief intervention in order to reduce problem drinking: a randomized controlled trial [PDF]
Lars J. Hansen+3 more
openalex +1 more source
In Vitro Modeling of Natural Killer Cell Cytotoxicity to Inform Personalized ALS Therapeutics
ABSTRACT Objective Natural killer (NK) cells might contribute to motor neuron death in amyotrophic lateral sclerosis (ALS) through direct cytotoxicity, a process that could be inhibited with the FDA‐approved JAK/STAT pathway inhibitor, tofacitinib. This study aimed to verify that tofacitinib can suppress NK cell cytotoxicity, investigate if immune cell
Benjamin J. Murdock+8 more
wiley +1 more source
Treatment of early Rheumatoid Arthritis with minocycline or placebo. Results of a Randomized, double‐blind, placebo‐controlled trial [PDF]
James R. O’Dell+15 more
openalex +1 more source
ABSTRACT Objective To compare the effectiveness of high‐efficacy treatments (HET) and low‐efficacy treatments (LET) in NMOSD patients with anti‐aquaporin‐4 antibodies (AQP4‐ab). Methods In this multi‐center study, we analyzed 183 AQP4‐ab seropositive NMOSD patients who received immunosuppressive treatments (IST).
Xiang Li+10 more
wiley +1 more source
Acupuncture with different frequencies for tobacco dependence: a randomized controlled trial. [PDF]
Shumin C+6 more
europepmc +1 more source
Individually randomized intervention trials for disease prevention and control [PDF]
Garnet L. Anderson, Ross L. Prentice
openalex +1 more source
Real‐World Comparison of High‐Efficacy Versus Non‐High‐Efficacy Therapies in Multiple Sclerosis
ABSTRACT Objective The choice of the first disease modifying treatment (DMT) in multiple sclerosis (MS) is a topic of great interest, and whether high‐efficacy DMTs should be the first choice remains debated. We compared treatment outcomes (no evidence of disease activity [NEDA] and its components) between treatment‐naïve relapsing–remitting MS (RRMS ...
Sarmad Al‐Araji+9 more
wiley +1 more source
Virtual Reality as an Adjunct to Pediatric Cast Removal: A Randomized Controlled Trial. [PDF]
Georgiadis AG+6 more
europepmc +1 more source
Calcium-enriched foods and bone mass growth in prepubertal girls: a randomized, double-blind, placebo-controlled trial. [PDF]
J.‐P. Bonjour+6 more
openalex +1 more source