Results 241 to 250 of about 4,106,658 (410)

Tryptophan‐sensing receptor GPR142 expression levels are directly regulated by proinflammatory cytokines in ghrelin‐producing cells

FEBS Open Bio, EarlyView.
GPR142, a tryptophan‐sensing receptor, stimulates gastrointestinal hormones like ghrelin and is linked to inflammation regulation. Proinflammatory cytokines suppress ghrelin production, while tryptophan levels decrease via IDO1 activation. Our findings reveal that proinflammatory cytokines directly regulate GPR142 expression in ghrelin‐producing cells,
Yoko Ueda, Hiroshi Iwakura, Takuya Ensho, Mika Bando‐Shimizu, Asako Doi, Norihiko Matsutani, Shuhei Morita, Hidefumi Inaba, Hiroyuki Ariyasu, Naoki Fukuda, Keiji Hayata, Toshiyasu Ojima, Masahiro Nishi, Taka‐aki Matsuoka, Hiroki Yamaue, Takashi Akamizu   +15 more
wiley   +1 more source

Reflections on Randomized Control Trials [PDF]

Social Science & Medicine, 2018
Deaton, Angus, Cartwright, Nancy
openaire   +5 more sources

A Prospective Randomized Control Trial Comparing Proximal Femoral Nail and Sliding Hip Screw in The Management of Trochanteric Fracture of The Femur

, 1970
NK Kam, A. C. Jain, P Nepal, Mahi Pal Singh, N Das   +4 more
openalex   +2 more sources

A Randomized, Controlled Trial of Prophylactic Ganciclovir for Cytomegalovirus Pulmonary Infection in Recipients of Allogeneic Bone Marrow Transplants [PDF]

, 1991
G. Schmidt, David Hořák, Joyce C. Niland, Steven R. Duncan, Scott Forman, John A. Zaia   +5 more
openalex   +1 more source

A potential tumor suppressor role of PLK2 in glioblastoma

FEBS Open Bio, EarlyView.
PLK2 was consistently downregulated in GBM tissues. Overexpression of PLK2 in GBM cell lines U87MG and U251 reduced their tumorigenic potential and enhanced cell cycle arrest and apoptosis. Suggesting that PLK2 overexpression could potentially be leveraged as a therapeutic strategy to inhibit tumor progression and enhance apoptosis, providing new ...
Xiangping Xia, Peirui Wang, Hua Xiao, Qishan Ran, Yan Li, Shengtao Yao   +5 more
wiley   +1 more source

Efficacy of Albendazole and Short-Course Prednisolone Treatment in Children with One or Two Ring-Enhancing Lesions of Neurocysticercosis: A Randomized Controlled Trial

, 1970
PK Swain, A Thapalial, R N Das, MS Dhaliwal, Kalpana Subedi   +4 more
openalex   +2 more sources

A multicenter randomized controlled trial of recombinant interferon-α2b in patients with acute transfusion-associated hepatitis C [PDF]

, 1994
Pietro Lampertico, Maria Grazia Rumi, R. Romeo, Antonio Craxı̀, R. Soffredini, Daniela Biassoni, Massimo Colombo   +6 more
openalex   +1 more source

Characterisation of the role played by ELMO1, GPR141 and the intergenic polymorphism rs918980 in Fuchs' dystrophy in the Indian population

FEBS Open Bio, EarlyView.
This study reports the upregulation of ELMO1 and GPR141 in human Fuchs' endothelial corneal dystrophy (FECD) corneal endothelium and ultraviolet A‐induced FECD mice model. A genetic association of an intergenic single nucleotide polymorphism rs918980 present between both genes is observed with FECD in the Indian population.
Susmita Sharma, Samar Kumar Basak, Sujata Das, Debasmita Pankaj Alone   +3 more
wiley   +1 more source

Treatment-control comparisons in platform trials including non-concurrent controls [PDF]

arXiv
Shared controls in platform trials comprise concurrent and non-concurrent controls. For a given experimental arm, non-concurrent controls refer to data from patients allocated to the control arm before the arm enters the trial. The use of non-concurrent controls in the analysis is attractive because it may increase the trial's power of testing ...
arxiv  

Evidence-Based Social Anxiety Intervention [PDF]

, 2016
Carey Dimmitt provides a brief overview of the article, Can School Counselors Deliver Cognitive-Behavioral Treatment for Social Anxiety Effectively? A Randomized Controlled Trial, which can be found in the Journal of Child Psychology and Psychiatry.
Dimmitt, Carey
core   +1 more source