Results 261 to 270 of about 989,911 (307)
Some of the next articles are maybe not open access.
American Journal of Roentgenology, 2004
(2004). Randomized controlled trials. Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders: Vol. 5, No. sup1, pp. 42-42.
Harald O, Stolberg +2 more
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(2004). Randomized controlled trials. Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders: Vol. 5, No. sup1, pp. 42-42.
Harald O, Stolberg +2 more
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Efficacy Randomized Controlled Trials
AJN, American Journal of Nursing, 2023Editor's note: This is the 14th article in a series on clinical research by nurses. The series is designed to be used as a resource for nurses to understand the concepts and principles essential to research. Each column will present the concepts that underpin evidence-based practice—from research design to data interpretation.
Bernadette, Capili, Joyce K, Anastasi
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Cluster randomized controlled trials
Journal of Evaluation in Clinical Practice, 2005AbstractCluster randomized controlled trial (RCT), in which groups or clusters of individuals rather than individuals themselves are randomized, are increasingly common. Indeed, for the evaluation of certain types of intervention (such as those used in health promotion and educational interventions) a cluster randomized trial is virtually the only ...
Suezann, Puffer +2 more
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Clinical Obstetrics and Gynecology, 1998
There are three main questions in health care: ‘what is going on?’, ‘why?’ and ‘what do we do about it?’. ‘What is going on?’ forms the basis for clinical assessment including history taking, examination, and diagnosis. The question ‘why?’ underlies all aetiological research from laboratory science to epidemiology. The cross-sectional, case–control and
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There are three main questions in health care: ‘what is going on?’, ‘why?’ and ‘what do we do about it?’. ‘What is going on?’ forms the basis for clinical assessment including history taking, examination, and diagnosis. The question ‘why?’ underlies all aetiological research from laboratory science to epidemiology. The cross-sectional, case–control and
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Randomized Controlled Trials in Pouchitis
Reviews on Recent Clinical Trials, 2012Pouchitis is the most common complication of Proctocolectomy with ileal pouch-anal anastomosis (IPAA) in patients with ulcerative colitis (UC). The diagnosis of pouchitis requires the presence of symptoms, together with characteristic endoscopic and histological abnormalities. The exact cause of pouchitis is not known.
GIONCHETTI, PAOLO +7 more
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2018
This chapter covers the current gold standard for evaluating the effectiveness of therapeutic interventions, the randomized controlled trial (RCT). Key features of the RCT, regardless of sub-type, are randomization, allocation concealment, and blinding.
Armour, Michael (R18715) +2 more
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This chapter covers the current gold standard for evaluating the effectiveness of therapeutic interventions, the randomized controlled trial (RCT). Key features of the RCT, regardless of sub-type, are randomization, allocation concealment, and blinding.
Armour, Michael (R18715) +2 more
+5 more sources
Randomized Controlled Trials 1: Design
2015Today's clinical practice relies on the application of well-designed clinical research, the gold standard test of an intervention being the randomized controlled trial. Principles of the randomized control trial include emphasis on the principal research question, randomization, blinding; definitions of outcome measures, of inclusion and exclusion ...
Bryan M, Curtis +2 more
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Beyond randomized, controlled trials
Current Opinion in Critical Care, 2004Most critical care physicians believe that randomized, controlled trials provide the best available evidence. This review contends that the importance of randomized, controlled trials was overemphasized and that they do not add more to knowledge and practice than physiologic and observational studies.
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2023
Abstract Randomized controlled trials (RCTs) are the preferred study design for assessing efficacy in clinical trials. This chapter describes the standard (two arm parallel-group) RCT design. In this chapter, why RCTs are considered the ‘gold’ standard design for comparing medical treatments is reviewed. The benefits of random allocation
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Abstract Randomized controlled trials (RCTs) are the preferred study design for assessing efficacy in clinical trials. This chapter describes the standard (two arm parallel-group) RCT design. In this chapter, why RCTs are considered the ‘gold’ standard design for comparing medical treatments is reviewed. The benefits of random allocation
openaire +1 more source
2016
Comparative effectiveness research generates evidence from observational studies and randomized controlled trials. For many clinical questions, the observational study is an efficient design. Sometimes inherent biases in observational studies yield false results that require refutation by a randomized controlled trial.
Nikhil R. Kalva, James F. Graumlich
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Comparative effectiveness research generates evidence from observational studies and randomized controlled trials. For many clinical questions, the observational study is an efficient design. Sometimes inherent biases in observational studies yield false results that require refutation by a randomized controlled trial.
Nikhil R. Kalva, James F. Graumlich
openaire +1 more source