Results 291 to 300 of about 3,612,030 (344)
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Randomized Controlled Trials in Pouchitis
Reviews on Recent Clinical Trials, 2012Pouchitis is the most common complication of Proctocolectomy with ileal pouch-anal anastomosis (IPAA) in patients with ulcerative colitis (UC). The diagnosis of pouchitis requires the presence of symptoms, together with characteristic endoscopic and histological abnormalities. The exact cause of pouchitis is not known.
GIONCHETTI, PAOLO +7 more
openaire +2 more sources
Pharmacogenomics (London), 2019
AIM To conducted a systematic review and meta-analysis of prospective, randomized controlled trials (RCTs) that examined pharmacogenetic-guided decision support tools (DSTs) relevant to depressive symptom remission in major depressive disorder (MDD ...
C. Bousman +4 more
semanticscholar +1 more source
AIM To conducted a systematic review and meta-analysis of prospective, randomized controlled trials (RCTs) that examined pharmacogenetic-guided decision support tools (DSTs) relevant to depressive symptom remission in major depressive disorder (MDD ...
C. Bousman +4 more
semanticscholar +1 more source
2018
This chapter covers the current gold standard for evaluating the effectiveness of therapeutic interventions, the randomized controlled trial (RCT). Key features of the RCT, regardless of sub-type, are randomization, allocation concealment, and blinding.
Armour, Michael (R18715) +2 more
+5 more sources
This chapter covers the current gold standard for evaluating the effectiveness of therapeutic interventions, the randomized controlled trial (RCT). Key features of the RCT, regardless of sub-type, are randomization, allocation concealment, and blinding.
Armour, Michael (R18715) +2 more
+5 more sources
Randomized Controlled Trials 1: Design
2015Today's clinical practice relies on the application of well-designed clinical research, the gold standard test of an intervention being the randomized controlled trial. Principles of the randomized control trial include emphasis on the principal research question, randomization, blinding; definitions of outcome measures, of inclusion and exclusion ...
Bryan M, Curtis +2 more
openaire +3 more sources
Beyond randomized, controlled trials
Current Opinion in Critical Care, 2004Most critical care physicians believe that randomized, controlled trials provide the best available evidence. This review contends that the importance of randomized, controlled trials was overemphasized and that they do not add more to knowledge and practice than physiologic and observational studies.
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2023
Abstract Randomized controlled trials (RCTs) are the preferred study design for assessing efficacy in clinical trials. This chapter describes the standard (two arm parallel-group) RCT design. In this chapter, why RCTs are considered the ‘gold’ standard design for comparing medical treatments is reviewed. The benefits of random allocation
openaire +1 more source
Abstract Randomized controlled trials (RCTs) are the preferred study design for assessing efficacy in clinical trials. This chapter describes the standard (two arm parallel-group) RCT design. In this chapter, why RCTs are considered the ‘gold’ standard design for comparing medical treatments is reviewed. The benefits of random allocation
openaire +1 more source
2016
Comparative effectiveness research generates evidence from observational studies and randomized controlled trials. For many clinical questions, the observational study is an efficient design. Sometimes inherent biases in observational studies yield false results that require refutation by a randomized controlled trial.
Nikhil R. Kalva, James F. Graumlich
openaire +1 more source
Comparative effectiveness research generates evidence from observational studies and randomized controlled trials. For many clinical questions, the observational study is an efficient design. Sometimes inherent biases in observational studies yield false results that require refutation by a randomized controlled trial.
Nikhil R. Kalva, James F. Graumlich
openaire +1 more source
Journal of the American Medical Association (JAMA), 2006
Jeffrey S. Berger +5 more
semanticscholar +1 more source
Jeffrey S. Berger +5 more
semanticscholar +1 more source
2013
This entry defines Randomized Control Trials (RCTs) and puts them in an historical context. It provides an understanding of the distinction between efficacy and effectiveness RCTs and explains why effectiveness trials are more relevant to social work interventions. The strengths and limitations of RCTs that use experimental designs are delineated.
openaire +1 more source
This entry defines Randomized Control Trials (RCTs) and puts them in an historical context. It provides an understanding of the distinction between efficacy and effectiveness RCTs and explains why effectiveness trials are more relevant to social work interventions. The strengths and limitations of RCTs that use experimental designs are delineated.
openaire +1 more source