Results 121 to 130 of about 188,812 (316)

The Effect of Preoperative Magnetic Resonance Imaging on Long-term Oncological Outcomes Following Radical Prostatectomy—A 12-year Follow-up of a Randomized Controlled Trial

European Urology Open Science
Background and objective: The effect of preoperative magnetic resonance imaging (MRI) on long-term oncological outcomes following robot-assisted laparoscopic prostatectomy (RALP) is uncertain.
Daniyal Noor, Eduard Baco, Peter M. Lauritzen, Viktor Berge, Kristina F. Galtung, Maciej Jacewicz, Lars Magne Eri, Erik Rud   +7 more
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Health visitors' assessments of parent–child relationships: a focus group study [PDF]

, 2008
<i>Background</i>: Health visitors (HVs), also known as public health nurses, in the UK provide a universal community-based service to preschool children and their parents.
Graham, Clair, Philip Wilson, Puckering, C., Monica Currie, Minnis, H., Currie, Monica, Barbour, R.S., Graham, C., Wilson, P., Clair Graham, Barbour, Rosaline S., Rosaline S. Barbour, Wilson, Philip, Minnis, Helen, Christine Puckering, Helen Minnis, Puckering, Christine, Currie, M.   +17 more
core   +1 more source

Evaluating Age, Sex, Racial, and Ethnic Representation in Acute Ischemic Stroke Trials, 2010 to 2020: A Systematic Review and Meta‐Analysis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Emily K. Acton, Mohammad Hossein Abbasi, Scott E. Kasner   +2 more
doaj   +1 more source

A Bayesian reevaluation of randomized controlled trials in assisted reproductive technology: quantifying evidence strength for null and alternative hypotheses

Frontiers in Endocrinology
IntroductionMany randomized controlled trials (RCTs) in assisted reproductive technology (ART) face widespread misinterpretation of statistically non-significant results within the conventional frequentist framework.
Jiayi Gao, Tian Tian, Kalbinur Kayimu, Yi Yuan, Yongyan Chen, Yu Fu, Rui Chen, Fang Liu, Yunjun Zhang, Yuanyuan Wang   +9 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Evaluating Complex Health Interventions With Randomized Controlled Trials: How Do We Improve the Use of Qualitative Methods? [PDF]

, 2019
Qualitative methods are underutilized in health intervention evaluation, and overshadowed by the importance placed on randomized controlled trials (RCTs).
Davis, K, Mannell, J
core  

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Outcomes of Mulligan Concept Applications in Obese Individuals with Chronic Mechanical Low Back Pain: A Randomized Controlled Trial

Life
Background: Various treatment modalities have been employed for mechanical low back pain (MLBP), but evidence of their efficacy varies greatly. Objectıve: This randomized controlled trial aimed to assess the outcomes of Mulligan concept applications ...
Muhammed Safa Cankaya, Omer Osman Pala
doaj   +1 more source