The axolotl's remarkable regenerative abilities decline with age, the causes may include the numerous repetitive elements within its genome. This study uncovers how Ty3 retrotransposons and coexpression networks involving muscle and immune pathways respond to aging and regeneration, suggesting that transposons respond to physiological shifts and may ...
Samuel Ruiz‐Pérez+8 more
wiley +1 more source
Inspiratory muscle training for chronic critically ill patients: a systematic review and meta-analysis of randomized controlled trials. [PDF]
Chagas GRD+5 more
europepmc +1 more source
Adverse events and safety issues associated with physical activity and exercise for adults with osteoporosis and osteopenia: A systematic review of observational studies and an updated review of interventional studies [PDF]
Clark, Emma M.+7 more
core +3 more sources
Targeting RAGE with Nanobodies for Molecular Imaging of Cancers and Alzheimer's Disease
RAGE‐specific nanobodies were isolated via phage display and characterized by ELISA, cell ELISA, and SPR. In vivo imaging in renal carcinoma and Alzheimer's disease mouse models demonstrated that NbF8, the highest‐affinity clone, selectively targeted RAGE‐overexpressing tumors and brain tissues, highlighting its potential as a molecular imaging agent ...
Guangfeng Liang+13 more
wiley +1 more source
Editorial: Rehabilitation interventions for mild traumatic brain injury. [PDF]
Anwar F.
europepmc +1 more source
The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li+10 more
wiley +1 more source
Development of a core outcome set for trials for management of oral submucous fibrosis (OSFCOS): A consensus study protocol. [PDF]
Gondivkar SM+4 more
europepmc +1 more source
EFFICIENCY OF TOPICAL PHENYTOIN ON HEALING IN DIABETIC ULCER: A RANDOMIZED CONTROL TRIAL [PDF]
Solaiappan Jeevaraman+1 more
openaire +1 more source
In vitro cancer models are advantageous for studying important processes such as tumorigenesis, cancer growth, invasion, and metastasis. The complexity and biological relevance increase depending on the model structure, organization, and composition of materials and cells.
Kyndra S. Higgins+2 more
wiley +1 more source
Research Trends and Hotspots of Acupuncture Therapy on Allergic Diseases From 2004 to 2024: A Bibliometric Analysis. [PDF]
Lv Y+6 more
europepmc +1 more source