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Topical ketorolac as an adjunctive treatment with intravitreal bevacizumab in the management of diabetic macular edema: A double-masked placebo-controlled randomized clinical trial

Graefe's Archive for Clinical and Experimental Ophthalmology, 2021
To evaluate the additional effect of ketorolac eye drops on therapeutic effects of intravitreal Bevacizumab in patients with diabetic macular edema (DME) METHODS: In a randomized clinical trial, 50 patients with center involved DME (macular thickness ≥ 300 microns accompanied by decreased VA (24 
Homayoun Nikkhah   +6 more
openaire   +2 more sources

Efficacy and Safety of Topical Pidobenzone 4% as Adjuvant Treatment for Solar Lentigines: Result of a Randomized, Controlled, Clinical Trial

Dermatology, 2016
<b><i>Background/Objective:</i></b> This study aims at the evaluation of the efficacy and safety of a combination therapy based on pidobenzone 4% and fractional CO<sub>2</sub> laser or cryotherapy in the treatment of solar lentigines and the prevention of eventual posttreatment hyperchromia. <b><i>Methods:
Anna, Campanati   +9 more
openaire   +2 more sources

Comparison of Oral Voriconazole Versus Oral Ketoconazole as an Adjunct to Topical Natamycin in Severe Fungal Keratitis: A Randomized Controlled Trial

Cornea, 2017
Purpose: To compare the efficacy of oral voriconazole (VCZ) with oral ketoconazole (KCZ) as an adjunct to topical natamycin in severe fungal keratitis. Methods: Fifty eyes of 50 patients with proven severe fungal keratitis, (>5 mm size, involving >4 mm central cornea and > ...
Namrata, Sharma   +8 more
openaire   +2 more sources

2-Octyl Cyanoacrylate Topical Adhesive as an Alternative to Subcuticular Suture for Skin Closure After Total Knee Arthroplasty: A Randomized Controlled Trial in the Same Patient

The Journal of Arthroplasty, 2021
The 2-octyl cyanoacrylate topical adhesive with flexible self-adhesive polyester mesh (Dermabond Prineo) is becoming widely used in many surgical fields. However, no prior studies have tested the efficacy and safety of this topical adhesive compared with subcuticular suture in the same patient.
Keun Young Choi   +5 more
openaire   +2 more sources

Is topical antimycotic treatment useful as adjuvant therapy for flexural atopic dermatitis: randomized, double‐blind, controlled trial using one side of the elbow or knee as a control

International Journal of Dermatology, 2008
Abstract Background  Certain factors are known to cause exacerbation of atopic dermatitis (AD), e.g. soap, detergent, dry skin, staphylococcal colonization, and herpes infection. Other factors are suspected, but not yet proven, e.g. yeasts belonging to the Malassezia
Alson W K, Wong   +2 more
openaire   +2 more sources

The role of the topical nasal decongestant oxymetazoline as a novel therapeutic option for post‐acne erythema: A split‐face, double‐blind, randomized, placebo‐controlled trial

The Journal of Dermatology, 2023
AbstractPost‐acne erythema (PAE) is one of the most common sequelae of acne inflammation. Unfortunately, the treatment of PAE remains challenging due to limited effective topical treatments. The objectives of this study were to evaluate the efficacy and safety of topical oxymetazoline hydrochloride (OxH) 0.05% solution for PAE.
Chanudda Washrawirul   +5 more
openaire   +2 more sources

Is Topical Vancomycin an Option? A Randomized Controlled Trial to Determine the Safety of the Topical Use of Vancomycin Powder in Preventing Postoperative Infections in Total Knee Arthroplasty, as Compared With Standard Postoperative Antibiotics

The Journal of Arthroplasty, 2023
The demand for total knee arthroplasties (TKAs) is expected to rise in the coming decades, increasing the burden of periprosthetic joint infections (PJIs). The use of intrawound vancomycin powder (VP) has proven to be effective in reducing the incidence of PJIs after spinal surgery. That said, its effectiveness in TKA remains unclear.
Wesam, Abuzaiter   +7 more
openaire   +2 more sources

Effectiveness of topical anesthesia as an adjuvant to local anesthetic injection during open surgical release of trigger digit: a randomized controlled trial

2023
Background: Open trigger digit release in adult is a common hand surgery. Most of the patients considered local anesthetic injection was the most painful step during the procedure. Topical anesthetic drug was not routinely used in the hand surgery. The study on its effectiveness in open trigger digit release has never been studied before. Objective:
openaire   +1 more source

Assessing the efficacy of oral tranexamic acid as an adjuvant to triple combination topical treatment in melasma: a meta-analysis of randomized controlled trials

Clinical and Experimental Dermatology
Abstract Melasma is a skin pigmentation disorder that lacks consistent treatment success, despite various methods used. Tranexamic acid (TXA) has shown hypopigmentation properties, but whether its administration should be combined with standard treatment has yet to be clarified.
Ocílio, Ribeiro Gonçalves   +8 more
openaire   +2 more sources

Topic: AS08-Treatment/AS08f-Clinical trials – Phase II-III: SELECT-MDS-1 TRIAL IN PROGRESS: A PHASE 3 RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL OF TAMIBAROTENE/AZACITIDINE VS PLACEBO/AZACITIDINE IN NEWLY DIAGNOSED (ND) ADULT PATIENTS SELECTED FOR RARA-POSITIVE HR-MDS

open access: closed, 2023
A. Dezern   +18 more
openalex   +1 more source

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