Results 271 to 280 of about 43,824,661 (311)
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Topical Cyclosporin A in the treatment of acute graft rejection: a randomized controlled trial
Clinical & Experimental Ophthalmology, 2008AbstractBackground: Corneal graft rejection is the commonest cause of graft failure. Currently, intensive topical steroid is the treatment for graft rejection. We hypothesized that the use of topical Cyclosporin A (CsA) 0.05%, specifically Restasis (Allergan) in addition to intensive steroids would aid in the reversal and treatment of endothelial ...
Alexander, Poon +3 more
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A Randomized Controlled Trial of Topical Analgesia Posthemorrhoidectomy (TAPH Trial)
Diseases of the Colon & RectumBACKGROUND: Postoperative pain remains the greatest problem after hemorrhoidectomy. Pain is hypothesized to arise from bacterial infection, sphincter spasm, and local inflammation. OBJECTIVE: This trial was conducted to assess the effects of metronidazole, diltiazem, and lidocaine ...
James Z, Jin +9 more
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American Journal of Therapeutics, 2021
Background: Effect of nifedipine on pressure ulcer (PU) healing has not been evaluated in the human subjects yet. Study question: In this study, the effect of topical application of nifedipine 3% ointment on PU healing in critically ill patients was investigated.
Hedieh, Zolfagharnezhad +4 more
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Background: Effect of nifedipine on pressure ulcer (PU) healing has not been evaluated in the human subjects yet. Study question: In this study, the effect of topical application of nifedipine 3% ointment on PU healing in critically ill patients was investigated.
Hedieh, Zolfagharnezhad +4 more
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Topical Tranexamic Acid in Breast Reconstruction: A Double-Blind Randomized Controlled Trial
Plastic & Reconstructive Surgery, 2023Background: Excess fluid accumulation (seroma/hematoma) around the breast implant after reconstruction can lead to significant complications. Topical administration of tranexamic acid (TXA) may reduce fluid accumulation and reduce postoperative complications.
Tyler, Safran +4 more
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Topical diclofenac therapy for osteoarthritis: a meta-analysis of randomized controlled trials
Clinical Rheumatology, 2015The objective of this study was to evaluate the efficacy and safety of topical diclofenac therapy for osteoarthritis (OA). A meta-analysis of randomized controlled trials was conducted. A comprehensive literature search, covering the databases of Medline, the Cochrane Central Register of Controlled Trials, and EMBASE, was conducted in September 2014 to
Zhen-han Deng +7 more
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Topical cyclosporin in oral lichen planus: a controlled, randomized, prospective trial
British Journal of Dermatology, 2006The published studies of topical cyclosporin (CyA) therapy in chronic oral lichen planus (OLP) have shown conflicting results. We report an investigator-blinded study of 13 patients with OLP, who were randomly assigned to treatment with CyA (500 mg as a swish-and-spit medication for 5 min three times daily) or a corticosteroid oral paste (triamcinolone
P, Sieg +4 more
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Topical Anesthetics for Dermal Instrumentation: A Systematic Review of Randomized, Controlled Trials
Annals of Emergency Medicine, 2005We compare the analgesic efficacy of topical anesthetics for dermal instrumentation with conventional infiltrated local anesthesia and also compare topically available amide and ester agents with a eutectic mixture of local anesthetics (EMLA).We conducted a systematic review of randomized, controlled trials.
Anthony, Eidelman +3 more
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Topical Analgesia for Endometrial Biopsy
Obstetrics & Gynecology, 2005To estimate whether benzocaine spray applied to the cervix and the endocervical canal before performing office endometrial biopsy improves patient comfort during the procedure.Eighty-eight women were randomly assigned to receive either 20% benzocaine spray or placebo to the outside of the cervix and into the endocervical canal before an endometrial ...
Jon I, Einarsson +2 more
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Acta Ophthalmologica, 2018
AbstractPurposeTo compare topical cyclosporine‐A 2% eye drop (Cs‐A) with prednisolone acetate 1% eye drop for treatment of herpetic stromal keratitis (HSK).MethodsIn this randomized clinical trial, 38 eyes of 33 patients with HSK were randomly assigned to receive either 2% Cs‐A or 1% prednisolone acetate eye drops.
Alireza Peyman +4 more
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AbstractPurposeTo compare topical cyclosporine‐A 2% eye drop (Cs‐A) with prednisolone acetate 1% eye drop for treatment of herpetic stromal keratitis (HSK).MethodsIn this randomized clinical trial, 38 eyes of 33 patients with HSK were randomly assigned to receive either 2% Cs‐A or 1% prednisolone acetate eye drops.
Alireza Peyman +4 more
openaire +2 more sources
Topical Anesthesia in Cutaneous Head and Neck Surgery: A Randomized Controlled Trial
Otolaryngology–Head and Neck SurgeryAbstractObjectiveCutaneous head and neck surgery can safely and effectively be performed using local anesthetic (LA). However, optimizing pain management during LA administration is paramount for patient comfort and procedural efficacy. The primary objective of this study was to investigate the comparative effectiveness of EMLA cream and ethyl chloride
Rory, O'Neill +3 more
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