Results 271 to 280 of about 340,709 (315)

Topical Nifedipine for the Treatment of Pressure Ulcer: A Randomized, Placebo-Controlled Clinical Trial

American Journal of Therapeutics, 2021
Background: Effect of nifedipine on pressure ulcer (PU) healing has not been evaluated in the human subjects yet. Study question: In this study, the effect of topical application of nifedipine 3% ointment on PU healing in critically ill patients was investigated.
Hedieh, Zolfagharnezhad, Hossein, Khalili, Mostafa, Mohammadi, Somayeh, Niknam, Alireza, Vatanara   +4 more
openaire   +2 more sources

A Randomized Controlled Trial of Topical Analgesia Posthemorrhoidectomy (TAPH Trial)

Diseases of the Colon & Rectum
BACKGROUND: Postoperative pain remains the greatest problem after hemorrhoidectomy. Pain is hypothesized to arise from bacterial infection, sphincter spasm, and local inflammation. OBJECTIVE: This trial was conducted to assess the effects of metronidazole, diltiazem, and lidocaine ...
James Z, Jin, Weisi, Xia, Runzhe, Gao, Alain C, Vandal, Maree, Weston, Lincoln, Israel, Andrew, Connolly, Primal Parry, Singh, Darren, Svirskis, Andrew, Hill   +9 more
openaire   +2 more sources

Topical cyclosporin in oral lichen planus: a controlled, randomized, prospective trial

British Journal of Dermatology, 2006
The published studies of topical cyclosporin (CyA) therapy in chronic oral lichen planus (OLP) have shown conflicting results. We report an investigator-blinded study of 13 patients with OLP, who were randomly assigned to treatment with CyA (500 mg as a swish-and-spit medication for 5 min three times daily) or a corticosteroid oral paste (triamcinolone
P, Sieg, H, Von Domarus, V, Von Zitzewitz, H, Iven, L, Färber   +4 more
openaire   +2 more sources

Topical diclofenac therapy for osteoarthritis: a meta-analysis of randomized controlled trials

Clinical Rheumatology, 2015
The objective of this study was to evaluate the efficacy and safety of topical diclofenac therapy for osteoarthritis (OA). A meta-analysis of randomized controlled trials was conducted. A comprehensive literature search, covering the databases of Medline, the Cochrane Central Register of Controlled Trials, and EMBASE, was conducted in September 2014 to
Zhen-han Deng, Chao Zeng, Ye Yang, Yu-sheng Li, Jie Wei, Tuo Yang, Hui Li, Guang-hua Lei   +7 more
openaire   +2 more sources

Topical Tranexamic Acid in Breast Reconstruction: A Double-Blind Randomized Controlled Trial

Plastic & Reconstructive Surgery, 2023
Background: Excess fluid accumulation (seroma/hematoma) around the breast implant after reconstruction can lead to significant complications. Topical administration of tranexamic acid (TXA) may reduce fluid accumulation and reduce postoperative complications.
Tyler, Safran, Joshua, Vorstenbosch, Alex, Viezel-Mathieu, Peter, Davison, Tassos, Dionisopoulos   +4 more
openaire   +2 more sources

A Randomized Vehicle-Controlled Trial of Topical Capsaicin in the Treatment of Postherpetic Neuralgia

Survey of Anesthesiology, 1994
A large double-blind, vehicle-controlled study of 143 patients with chronic postherpetic neuralgia (PHN) was performed to evaluate the degree of efficacy of topically applied capsaicin 0.075% cream. In addition, the safety and efficacy of long-term application of topical capsaicin in PHN was assessed by following patients in an open-label study for up ...
C P, Watson, K L, Tyler, D R, Bickers, L E, Millikan, S, Smith, E, Coleman   +5 more
openaire   +2 more sources

Topical Anesthetics for Dermal Instrumentation: A Systematic Review of Randomized, Controlled Trials

Annals of Emergency Medicine, 2005
We compare the analgesic efficacy of topical anesthetics for dermal instrumentation with conventional infiltrated local anesthesia and also compare topically available amide and ester agents with a eutectic mixture of local anesthetics (EMLA).We conducted a systematic review of randomized, controlled trials.
Anthony, Eidelman, Jocelyn M, Weiss, Joseph, Lau, Daniel B, Carr   +3 more
openaire   +2 more sources

A Randomized Controlled Trial of Topical Cannabidiol for the Treatment of Thumb Basal Joint Arthritis

The Journal of Hand Surgery, 2022
Since the passage of the Agricultural Improvement Act of 2018, hand surgeons have increasingly encountered patients seeking counseling on over-the-counter, topical cannabidiol (CBD) for the treatment of pain. To this end, we designed a human clinical trial to investigate the therapeutic potential of CBD for the treatment of pain associated with thumb ...
John T, Heineman, Grace L, Forster, Kristen L, Stephens, Patrick S, Cottler, Michael P, Timko, Brent R, DeGeorge   +5 more
openaire   +2 more sources

Topical Analgesia for Endometrial Biopsy

Obstetrics & Gynecology, 2005
To estimate whether benzocaine spray applied to the cervix and the endocervical canal before performing office endometrial biopsy improves patient comfort during the procedure.Eighty-eight women were randomly assigned to receive either 20% benzocaine spray or placebo to the outside of the cervix and into the endocervical canal before an endometrial ...
Jon I, Einarsson, Gwendolyn, Henao, Amy E, Young   +2 more
openaire   +2 more sources

Topical cyclosporine‐A versus prednisolone for herpetic stromal keratitis: a randomized controlled trial

Acta Ophthalmologica, 2018
AbstractPurposeTo compare topical cyclosporine‐A 2% eye drop (Cs‐A) with prednisolone acetate 1% eye drop for treatment of herpetic stromal keratitis (HSK).MethodsIn this randomized clinical trial, 38 eyes of 33 patients with HSK were randomly assigned to receive either 2% Cs‐A or 1% prednisolone acetate eye drops.
Alireza Peyman, Mohamadreza Nayebzadeh, Mohamadreza Peyman, Natalie A. Afshari, Mohsen Pourazizi   +4 more
openaire   +2 more sources