Results 281 to 290 of about 340,709 (315)

Topical Sucralfate Treatment of Anal Fistulotomy Wounds: A Randomized Placebo-Controlled Trial

Diseases of the Colon & Rectum, 2011
Sucralfate is a cytoprotective agent which adheres to mucoproteins and forms a protective barrier at wound sites. In oral form it is a common ulcer medication, and as a topical preparation it has been used to treat a wide variety of wounds.The present study was designed to evaluate the effectiveness and safety of topical sucralfate in wound healing ...
Pravin J, Gupta, Purushottam S, Heda, Subhash A, Shrirao, Surekha S, Kalaskar   +3 more
openaire   +2 more sources

Effects of Topical Antifibrinolytics in Endoscopic Sinus Surgery: A Pilot Randomized Controlled Trial

American Journal of Rhinology, 2007
Background Bleeding in endoscopic sinus surgery (ESS) may increase the risk of intraoperative complications and is associated with poorer outcomes Antifibrinolytic agents have been shown to reduce bleeding if administered systemically. The aim of this study was to determine the effect of topical epsilon-aminocaproic acid (EACA) and tranexamic acid (TA)
Athanasiadis, T., Beule, A., Wormald, P.
openaire   +3 more sources

A randomized controlled trial of R-salbutamol for topical treatment of discoid lupus erythematosus

British Journal of Dermatology, 2009
In a recent open pilot trial, R-salbutamol sulphate, a well-known molecule with anti-inflammatory effects, was tested successfully on patients with therapy-resistant discoid lupus erythematosus (DLE).To compare the efficacy and safety of R-salbutamol cream 0.5% vs.
Jemec, G B E, Ullman, S, Goodfield, M, Bygum, A, Olesen, A B, Berth-Jones, J, Nyberg, F, Cramers, M, Faergemann, J, Andersen, P, Kuhn, A, Ruzicka, T   +11 more
openaire   +3 more sources

Topical Anesthesia in Cutaneous Head and Neck Surgery: A Randomized Controlled Trial

Otolaryngology–Head and Neck Surgery
AbstractObjectiveCutaneous head and neck surgery can safely and effectively be performed using local anesthetic (LA). However, optimizing pain management during LA administration is paramount for patient comfort and procedural efficacy. The primary objective of this study was to investigate the comparative effectiveness of EMLA cream and ethyl chloride
Rory, O'Neill, Adrinda, Affendi, Nathaniel, McHugh, Liam, Skinner   +3 more
openaire   +2 more sources

Randomized Controlled Trial of Topical Hyperbaric Oxygen for Treatment of Diabetic Foot Ulcers

Diabetes Care, 1988
The effect of 2 wk of topical hyperbaric oxygen (THO) treatment on the healing of diabetic foot ulcers without associated gangrene was evaluated in a prospective, controlled, and randomized manner in 28 patients. There were 12 patients in the THO group (group 1) and 16 in the control group (group 2).
C A, Leslie, F L, Sapico, V J, Ginunas, R H, Adkins   +3 more
openaire   +2 more sources

A pilot randomized controlled trial of topical androgen treatment in dry eye

The Ocular Surface
To evaluate the safety and efficacy of eyelid androgen gel application to treat moderate to severe dry eye disease.Twenty four eyes of 24 subjects (12 eyes per arm) were randomized to either eyelid testosterone or vehicle gel. Subjects received either 17β-Hydroxyandrost-4-en-3-one) 4.5 % wt./wt.
Jay Ruzhang, Jiang, Rima, Khankan, William H, Ridder, Andrew Loc, Nguyen, Jerry R, Paugh   +4 more
openaire   +2 more sources

Effect of topical diclofenac on postoperative photorefractive keratectomy pain: a randomized, controlled trial

Clinical & Experimental Ophthalmology, 2014
AbstractBackgroundA major disadvantage of photorefractive keratectomy is postoperative pain and discomfort. This study aims to evaluate whether topical diclofenac 0.1% therapy adds any extra benefit to systemic diclofenac in controlling pain after photorefractive keratectomy.DesignProspective randomized, double‐masked clinical trial applied in the ...
Alireza, Eslampoor, Asieh, Ehsaei, Mojtaba, Abrishami   +2 more
openaire   +2 more sources

Topical Treatments for Melasma: A Systematic Review of Randomized Controlled Trials

Journal of drugs in dermatology : JDD, 2020
Background: Melasma is an acquired skin disease characterized by symmetric hyperpigmentation on sun-exposed areas, particularly on the face. Recently, there has been tremendous scientific interest in novel, safe, and effective topical agents to manage melasma.
Evan, Austin, Julie K., Nguyen, Jared, Jagdeo   +2 more
openaire   +1 more source

A RANDOMIZED CONTROLLED TRIAL OF INTRACAMERAL LIDOCAINE DURING PHACOEMULSIFICATION UNDER TOPICAL ANESTHESIA

Evidence-Based Eye Care, 2000
To test the hypothesis that adjunctive intracameral 1% lidocaine reduces intraoperative pain during phacoemulsification using topical anesthesia.Prospective, double-masked, randomized, controlled trial.A total of 200 patients undergoing routine phacoemulsification under topical 1% tetracaine were studied.Randomization to 0.5 ml intracameral ...
J E, Boulton, A, Lopatatzidis, J, Luck, R M, Baer   +3 more
openaire   +2 more sources

A randomized, placebo-controlled trial of topical cyclosporin a in steroid-dependent atopic keratoconjunctivitis,

Ophthalmology, 1998
This study aimed to investigate the therapeutic effect of topical cyclosporin A (CsA) 2% in maize oil as a steroid-sparing agent in steroid-dependent atopic keratoconjunctivitis.Prospective, randomized, double-masked, placebo-controlled trial.Twenty-one patients with steroid-dependent atopic keratoconjunctivitis were studied.Patients used either ...
M, Hingorani, L, Moodaley, V L, Calder, R J, Buckley, S, Lightman   +4 more
openaire   +2 more sources