Results 121 to 130 of about 1,011,036 (303)

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Multivariate analysis of randomized response data

, 2008
The thesis describes the multivariate analysis of randomized response data. Randomized response was introduced in 1965 as an interview technique to eliminate evasive response behavior (Warner, 1965).
Methodology and statistics for the behavioural and social sciences, Cruyff, M.J.L.F., Afd methoden en statistieken   +2 more
core  

Effect of a Proposed Trastuzumab Biosimilar Compared With Trastuzumab on Overall Response Rate in Patients With ERBB2 (HER2)–Positive Metastatic Breast Cancer. A Randomized Clinical Trial [PDF]

, 2017
IMPORTANCE Treatment with the anti-ERBB2 humanized monoclonal antibody trastuzumab and chemotherapy significantly improves outcome in patients with ERBB2 (HER2)–positive metastatic breast cancer; a clinically effective biosimilar may help increase ...
Herson, Jay, Waller, Cornelius F., Baramidze, Kakhaber, Sriuranpong, Virote, Kothekar, Mudgal, Barve, Abhijit, Manikhas, Alexey, Ruiz, Eduardo P Yanez, Hernandez-Bronchud, Miguel, Sharma, Rajiv, Mukhametshina, Guzel, Loganathan, Subramanian, Pennella, Eduardo, Rugo, Hope S., Vynnychenko, Ihor, Nemsadze, Gia, Ray, Sirshendu, Abesamis Tiambeng, Maria Luisa T., Bondarenko, Igor, Parra, Joseph D, Mamillapalli, Gopichand, Yuan, Jinyu, Baczkowski, Mark, Akewanlop, Charuwan   +23 more
core  

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

On partial randomized response model using ranked set sampling. [PDF]

PLoS One, 2022
Abbasi AM, Shad MY, Ahmed A.
europepmc   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Comment on "Recreational Athletes' Use of Performance‑Enhancing Substances: Results from the First European Randomized Response Technique Survey". [PDF]

Sports Med Open, 2023
Petrou M, Lazuras L.
europepmc   +1 more source

Increasing response rates to lifestyle surveys: a pragmatic evidence review

, 2011
Aims: Lifestyle surveys are often a key component of a local Joint Strategic Needs Assessment (JSNA), undertaken to inform public health planning. They are usually administered to a large number of people in order to provide a comprehensive profile of ...
S. McCluskey, Topping, A. E., Topping, Annie, McCluskey, S., McCluskey, Serena, Topping, AE; id_orcid, McCluskey, S, AE Topping   +7 more
core   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Recreational Athletes' Use of Performance-Enhancing Substances: Results from the First European Randomized Response Technique Survey. [PDF]

Sports Med Open, 2023
Christiansen AV, Frenger M, Chirico A, Pitsch W.   +3 more
europepmc   +1 more source