Results 141 to 150 of about 1,011,036 (303)

Randomized Comparison of Sirolimus and Paclitaxel Drug-Eluting Stents for Long Lesions in the Left Anterior Descending Artery: an Intravascular Ultrasound Study

open access: yes, 2008
The objective of this prospective randomized study was to verify whether the superiority of the sirolimus-eluting stent (SES) in inhibiting neointimal hyperplasia could be demonstrated in complex coronary lesions. The SES was compared with the paclitaxel-
BRANCHITTA, GIULIA
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Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Increasing response rates to lifestyle surveys: a review of methodology and 'good practice'.

open access: yes
Background Lifestyle surveys are traditionally used for collecting detailed population information about individual behaviours that impact on health.
Topping, Annie, McCluskey, Serena
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Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

The Effect of High School Matriculation Awards: Evidence from Randomized Trials [PDF]

open access: yes
In Israel, as in many other countries, a high school matriculation certificate is required by universities and some jobs. In spite of the certificate's value, Israeli society is marked by vast differences in matriculation rates by region and ...
Victor Lavy, Joshua D. Angrist
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Asking sensitive questions: Possibilities and limits of randomized response and other techniques in different survey modes [PDF]

open access: yes, 2013
In our project within the DFG Priority Programme on Survey Methodology (SPP 1292) we conducted various methodological studies on survey techniques for asking sensitive questions.
Krumpal, Ivar   +3 more
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Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

A Modified Stratified Randomized Response Techniques

open access: yes, 2014
This paper presents a modification of Kim and Warde’s (2004) Stratified Warner’s Randomized Response Technique (SWRRT) and Kim and Elam’s (2007) Stratified Unrelated Question Randomized Response Technique with known distribution (SURRT) using optimal ...
Johnson, O.O.   +2 more
core  

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Instrumental Variables Methods in Experimental Criminological Research: What, Why, and How? [PDF]

open access: yes
Quantitative criminology focuses on straightforward causal questions that are ideally addressed with randomized experiments. In practice, however, traditional randomized trials are difficult to implement in the untidy world of criminal justice. Even when
Joshua Angrist
core  

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