Results 121 to 130 of about 12,777,594 (289)
We study a generalization of the classical median finding problem to batched query case: given an array of unsorted $n$ items and $k$ (not necessarily disjoint) intervals in the array, the goal is to determine the median in {\em each} of the intervals in the array.
Sariel Har-Peled, S. Muthukrishnan 0001
openaire +3 more sources
Report for 1902 includes "reports of the Baltic Mining Company, Copper Range Company, Champion Copper Company, and Copper Range Railroad Company.Report year ends Dec. 31.Report for 1902 includes "reports of the Baltic Mining Company, Copper Range Company,
Baltic Mining Company. +4 more
core
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Rangeland Ecology & Management Table of Contents Volume 71, Number 5 (2018)
The Rangeland Ecology & Management archives are made available by the Society for Range Management and the University of Arizona Libraries.
Society for Range Management
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From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Vocalizations distinguish the cryptic giant hummingbird species and clarify range limits
Vocal traits are often essential for distinguishing phenotypically cryptic taxa. The hummingbird genus Patagona comprises two species that differ in important aspects of their ecology and physiology but that are near identical in plumage and morphology:
Bryce W Robinson +4 more
doaj +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
In this note we look into detail at the box-counting dimension of subordinators. Given that $X$ is a non-decreasing Levy process, which is not a compound Poisson process, we show that in the limit, the minimum number of boxes of size $δ$ that cover the range of $(X_s)_{s\leq t}$ is a.s.
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Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source

