Results 131 to 140 of about 10,550,867 (315)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Publications /

Latest issue consulted: 1980.Description based on: 1980; title from caption.Mode of access: Internet.Annual cumulation of: Publications (Pacific Southwest Forest and Range Experiment Station (Berkeley, Calif. : Quarterly),
Pacific Southwest Forest and Range Experiment Station (Berkeley, Calif.)
core  

Rangelands, Volume 44, Issue 3 (June 2022)

, 2022
Masthead/Table of ContentsThe Rangelands archives are made available by the Society for Range Management and the University of Arizona Libraries.
Society for Range Management
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The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Rangeland Ecology & Management Table of Contents Volume 71, Number 2 (2018)

, 2018
The Rangeland Ecology & Management archives are made available by the Society for Range Management and the University of Arizona Libraries.
Society for Range Management
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Ecologo-Geographic Distribution Patterns of the Italian Locust Calliptamus italicus (Linnaeus) (Orthoptera: Acrididae) in the Easternmost Part of Its Range

Insects
Grasshoppers (Acridoidea) are one of the most essential components of grassland ecosystems. They are mainly primary consumers and some of them, e.g., the Italian locust, may be very important pests.
Michael G. Sergeev, Muratbek K. Childebaev, Rong Ji, Vladimir V. Molodtsov, Natalya S. Baturina, Irina A. Van’kova, Marya N. Kim-Kashmenskaya, Kristina V. Popova, Vasily D. Zharkov, Oxana V. Yefremova   +9 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Distribution, ecology and conservation of the Potamogeton alpinus Balb. (Potamogetonaceae Bercht. & J. Presl) on the southern border of range in European Russia

Трансформация экосистем
Potamogeton alpinus Balb. is a Holarctic arctoboreal aquatic plant species. In European Russia, it is a common species in the tundra and taiga. We have found that the southern border of the main part of the range of P.
E.V. Ershkova, I.G. Esina, O.G. Grishutkin, A.V. Chkalov   +3 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source