Results 181 to 190 of about 10,550,867 (315)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Severe autoimmunity after checkpoint inhibitor therapy in a patient with autoimmune polyglandular syndrome type 1. [PDF]

JCEM Case Rep
Lim A, Peluso EM, Downs IA, Horwich BH, Velez-Velez MA, Lechner MG.   +5 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Prevalence of mental disorders in people with intellectual disabilities across the lifespan: umbrella review. [PDF]

BJPsych Open
Santambrogio J, Boido G, Marchetti M, Rudra S, Besana F, Francia E, Terrevazzi S, Papola D, Barbui C, Bertelli M, Clerici M, D'Agostino A, Marston L, Hassiotis A.   +13 more
europepmc   +1 more source

On the range of a derivation [PDF]

Pacific Journal of Mathematics, 1971
openaire   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

A Comparison of the Effects of the Timing of Resistance Exercise on Glucose Levels Within the Target Range in People With Type 1 Diabetes (TREX Study): A Randomized Crossover Trial. [PDF]

Diabetes Metab Res Rev
Ozairi ESA, Hamdan YG, Awadhi AAA, Otaibi NBA, Baqer AH, West DJ, Taliping DR, Kandari JAA, Gray SR.   +8 more
europepmc   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

3D Shape Reconstruction from Multiple Range Image Views

, 2006
Shape reconstruction of different three dimensional objects using multiple range images has evolved recently within the recent past. In this research shape reconstruction of a three dimensional object using multiple range image views is investigated ...
Ganapathi Annadurai, Kartick
core  

Spring-mediated cranioplasty for scaphocephaly: techniques and outcomes. [PDF]

Childs Nerv Syst
Guyler MR, Perrault DP, Naidu K, Lopez-Becerra S, Swanson JW, Bartlett SP, Taylor JA, Shakir S.   +7 more
europepmc   +1 more source