Results 71 to 80 of about 907,352 (310)

A self-organizing state-space-model approach for parameter estimation in Hodgkin-Huxley-type models of single neurons [PDF]

open access: yes, 2012
Traditional approaches to the problem of parameter estimation in biophysical models of neurons and neural networks usually adopt a global search algorithm (for example, an evolutionary algorithm), often in combination with a local search method (such as ...
Aston, John A. D.   +16 more
core   +1 more source

Validation of PeneloPET positron range estimations [PDF]

open access: yesIEEE Nuclear Science Symposuim & Medical Imaging Conference, 2010
Proceeding of: 2010 IEEE Nuclear Science Symposium, Medical Imaging Conference and 17th Room Temperature Semiconductor Detector Workshop (IEEE), Knoxville, Tennessee, USA, October 30 - November 6, 2010 Positron range depends on the materials in which positron propagates and on positron emitter isotope.
Cal González, Jacobo   +5 more
openaire   +2 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Robust estimation of the Hurst parameter and selection of an onset scaling. [PDF]

open access: yes, 2009
We consider the problem of estimating the Hurst parameter for long-range dependent processes using wavelets. Wavelet techniques have been shown to effectively exploit the asymptotic linear relationship that forms the basis of constructing an estimator ...
Park, Cheolwoo, Park, Juhyun
core  

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Efficient Range Estimation in Beat Radio Interferometry

open access: yesIEEE Access, 2017
The beat radio interferometry (BRI) is a novel ranging scheme that achieves high accuracy with low-cost devices. A major problem with BRI is the lack of an efficient range estimation method that is valid in general measurement configurations and ...
Bing Xu, Wangdong Qi, Li Wei, Su Zhang
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Defining the accuracy of real-world range estimations of an electric vehicle [PDF]

open access: yes, 2014
Range anxiety is a major barrier for the mass adoption of electric vehicles (EVs), a contributing factor to this is the variability of the predicted range remaining presented to the driver in the vehicle.
McGordon, Andrew   +5 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

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