Results 91 to 100 of about 2,973,168 (216)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Comparison of Actual Hybrid-Electric Flights with a Digital Twin in a Preliminary Aircraft Design Environment

Aerospace
To tackle climate change, aircraft designers envision new aircraft concepts which promise to reduce greenhouse gas emissions and enable greener flights. One option is hybrid-electric propulsion architectures.
Dominik Eisenhut, Andreas Bender, Niclas Grüning, Jonas Mangold, Andreas Strohmayer   +4 more
doaj   +1 more source

BLUE filter with fused range estimation

The Journal of Engineering, 2019
The non-linear filter is subject to divergence for close-range target tracking; an adaptive best linear unbiased estimation (BLUE) filter with fused range estimation is presented.
Sheng Hu, Zhao Wen-bo, Tang Si-yuan
doaj   +1 more source

Magnitude estimation - The exponent and range of response [PDF]

Magnitude estimation judgments on space vehicle distance and responses studied according to stimulus ...
Markley, R. P.
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Application of Hybrid-Electric Propulsion to ‘Large-Cabin’ Business Aircraft

World Electric Vehicle Journal
This paper aims to fill a critical cap in hybrid-electric propulsion (HEP) research by investigating the feasibility of its application on a ‘large-cabin’ business aircraft by 2040, for which key requirements are a long range of at least 6297 km (3400 ...
Ambar Sarup
doaj   +1 more source

Coherent Tunneling and Instantons in Presence of Classical Chaos

, 2003
We consider the instanton approach to the problem of chaos assisted tunneling in the context of existing analytical and numerical results obtained in this field.
Kuvshinov, V. I., Kuzmin, A. V.
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Qualitative Prediction of End-to-End Delay in 5G Networks

IEEE Access
Accurate end-to-end (E2E) delay prediction is critical for optimizing network performance and ensuring quality of service in 5G networks. This paper investigates two complementary qualitative E2E delay prediction methodologies: a Bayesian approach based ...
Diyar Fadhil, Rodolfo Oliveira
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source