A hybrid method of correcting CBCT for proton range estimation with deep learning and deformable image registration. [PDF]
Phys Med Biol, 2023 Uh J +7 more
europepmc +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Letter to the Editor Regarding "Time in Range Estimation in Patients with Type 2 Diabetes is Improved by Incorporating Fasting and Postprandial Glucose Levels". [PDF]
Diabetes Ther, 2023 Aggarwal A, Kaur R.
europepmc +1 more source
Predicting Overprecision in Range Estimation.
, 2016 Overprecision (overconfidence in interval estimation) is a biaswith clear implications for economic outcomes in industriesreliant on forecasting possible ranges for future prices andunknown states of nature - such as mineral and petroleumexploration. Prior research has shown the ranges peopleprovide are too narrow given the knowledge they have – thatis,
Kaesler, Matthew +2 more
openaire +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
The evolutionary history and ancestral biogeographic range estimation of old-world Rhinolophidae and Hipposideridae (Chiroptera). [PDF]
BMC Ecol Evol, 2022 Chornelia A, Hughes AC.
europepmc +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
, 2009 This paper presents a method of recovering the 6 DoF pose (Cartesian position and angular\ud rotation) of a range sensor mounted on a mobile platform.
Williams, I. +5 more
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Mobile device-based Bluetooth Low Energy Database for range estimation in indoor environments. [PDF]
Sci Data, 2022 Pascacio P +3 more
europepmc +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source