Results 51 to 60 of about 17,718 (201)
Frontiers in MedicineBackgroundEvidence on the excretion of anti-VEGF drugs in human breast milk was very limited. Here we investigated the level of VEGF-A protein and free drug concentration of ranibizumab in serum and breast milk following intravitreal injection of ...
Jiaxuan Zhang +5 more
doaj +1 more source
Aging Cell, Volume 25, Issue 2, February 2026.MSC‐derived exosomes deliver lnc‐AGT‐3 to vascular endothelial cells, where it binds hnRNP K in the nucleus. This interaction inhibits p53 ubiquitination, enhancing p53 stabilization and transcriptional activation of anti‐angiogenic targets TSP1. Consequently, p53‐mediated signaling is potentiated, effectively suppressing choroidal neovascularization ...
Lingjie Kong +9 more
wiley +1 more source
Acta Ophthalmologica, Volume 104, Issue 1, Page 98-105, February 2026.Abstract Background Intravitreal Anti‐Vascular Endothelial Growth Factor (VEGF) rescues retinal vasculatures and prevents disease progression in patients with neovascular Age‐Related Macular Degeneration (nAMD). However, systemic anti‐VEGF may increase the risk of thromboembolic related complications including stroke and TIA. This study aims to explore
A. H. Falemban +5 more
wiley +1 more source
Treatment of age-related macular degeneration: focus on ranibizumab
Clinical Ophthalmology, 2008 Martin S Spitzer, Focke Ziemssen, Karl U Bartz-Schmidt, Faik Gelisken, Peter SzurmanTuebingen University Eye Center, University of Tuebingen, GermanyAbstract: Ranibizumab, a humanized antigen-binding fragment (Fab) that binds all isoforms of VEGF-A ...
Martin S Spitzer +4 more
doaj
Biomedical Papers, 2015 Aims: The aim of this communication was to evaluate ranibizumab in the treatment of wet age-related macular degeneration. Methods: Anonymised data on treatment efficacy and safety were consecutively entered into the Czech national database.
Oldrich Chrapek +8 more
doaj +1 more source
Acta Ophthalmologica, Volume 104, Issue 1, Page e1-e17, February 2026.Abstract Purpose Retinopathy of prematurity (ROP) is a major cause of childhood blindness, and selecting the optimal treatment between anti‐vascular endothelial growth factor (anti‐VEGF) and laser therapy is crucial. Understanding their impact on key outcomes, particularly mortality, is essential for informed clinical decision‐making.
Wei‐De Wang +10 more
wiley +1 more source
Sulphur Analogues of Homoisoflavonoids as Potential Treatments for Neovascular Eye Diseases
ChemMedChem, Volume 21, Issue 2, January 2026.Neovascular eye diseases are characterised by the abnormal growth of often fragile blood vessels in the eye. Treatment focuses on reducing angiogenesis as well as reducing oxidative stress induced inflammation, a key underlying cause. Synthetic sulphur analogues of naturally occurring homoisoflavonoids, synthesised in three steps, have shown promise as
Jacob D. Hiles +9 more
wiley +1 more source
Clinical Ophthalmology, 2012 Patrick D Williams,1 David Callanan,1 Wayne Solley,1 Robert L Avery,2 Dante J Pieramici,2 Tom Aaberg31Texas Retina Associates, Dallas, TX, 2California Retina Consultants and Research Foundation, Santa Barbara, CA, 3Retinal Associates, Grand Rapids, MI ...
Williams PD +5 more
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ClinicoEconomics and Outcomes Research, 2015 Stephane A Régnier,1 William Malcolm,2 Jennifer Haig,3 Weiguang Xue41Novartis Pharma AG, Basel, Switzerland; 2Novartis Pharmaceuticals UK Ltd, Frimley Business Park, UK; 3Optum, Burlington, ON, Canada; 4Optum, Uxbridge, UKBackground: Ranibizumab ...
Régnier SA +3 more
doaj
International Journal of Ophthalmology, 2014 AIM:To compare the efficacy and safety of combination of ranibizumab with photodynamic therapy (PDT) vs ranibizumab monotherapy in the treatment of age-related macular degeneration (AMD).METHODS:The Cochrane Central Register of Controlled Trials (CENTRAL)
Jun-Kang Si +9 more
doaj +1 more source