Results 91 to 100 of about 3,725,370 (324)

Polymorphisms within the RANK and RANKL Encoding Genes in Patients with Rheumatoid Arthritis: Association with Disease Progression and Effectiveness of the Biological Treatment [PDF]

, 2020
Joanna Wielińska, Katarzyna Kolossa, Jerzy Świerkot, Marta Dratwa, Milena Iwaszko, Bartosz Bugaj, Barbara Wysoczańska, Monika Chaszczewska-Markowska, Sławomir Jeka, Katarzyna Bogunia‐Kubik   +9 more
openalex   +1 more source

Vacuolar transport and function of Saccharomyces cerevisiae sterol ester hydrolase Tgl1

FEBS Letters, EarlyView.
Tgl1, one of yeast sterol ester hydrolases, had been found on the lipid droplets where sterol esters are mainly stored. This study revealed that Tgl1 is transported into the vacuole depending on the ESCRT‐I–III complex, and that it exhibits intra‐vacuolar sterol ester hydrolase activity.
Takumi Nakatsuji, Kosuke Shiraishi, Chuqian Wang, Hiroya Yurimoto, Yasuyoshi Sakai, Masahide Oku   +5 more
wiley   +1 more source

The role of fibroblast growth factors in cell and cancer metabolism

FEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

Rank Intersectionality and Othello

Multicultural Shakespeare
As a crucial concept in critical theory, intersectionality satisfies a need within global Shakespeare reception studies. The reason for this is the way it permits cross-currents between conceptions of race and gender in particular; it also allows for an ...
Paul Innes
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Ranking the rankings

, 2014
In een academische wereld die steeds competitiever wordt, willen we graag weten wat ‘de beste’ universiteit is. Verschillende rankings bedienen ons op onze wenken, waaronder Times Higher Education, Sjanghai, QS en Leiden. De kritiek op die lijsten is echter niet mals, ook omdat universiteiten graag selectief shoppen in de resultaten.
Sikkema, A., van Ruitenbeek, H.C.G., Gerritsma, W., Wouters, P.   +3 more
openaire   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Nonnegative Rank vs. Binary Rank

, 2016
Motivated by (and using tools from) communication complexity, we investigate the relationship between the following two ranks of a $0$-$1$ matrix: its nonnegative rank and its binary rank (the $\log$ of the latter being the unambiguous nondeterministic communication complexity).
openaire   +2 more sources

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

Comparative Analysis of Web Visibility using SEO Tools And Its Effect on Website Improvement [PDF]

International Journal of Web Research
The growing accessibility of web pages to internet users, coupled with the increasing reliance on search engines for daily tasks, underscores the rising importance of search engine optimization (SEO).
Hadis Shafaei, Mohammad Taheri
doaj   +1 more source