Results 61 to 70 of about 604,826 (264)

Analyzing Space-Time Dynamics of Theft Rates Using Exchange Mobility

open access: yesISPRS International Journal of Geo-Information, 2018
A critical issue in the geography of crime is the quantitative analysis of the spatial distribution of crimes which usually changes over time. In this paper, we use the concept of exchange mobility across different time periods to determine the spatial ...
Yicheng Tang   +4 more
doaj   +1 more source

Exceptional in so Many Ways—Discovering Descriptors That Display Exceptional Behavior on Contrasting Scenarios

open access: yesIEEE Access, 2020
The current state of the art in supervised descriptive pattern mining is very good in automatically finding subsets of the dataset at hand that are exceptional in some sense.
Jose Maria Luna   +3 more
doaj   +1 more source

Rank intraclass correlation for clustered data [PDF]

open access: bronze, 2023
Shengxin Tu   +3 more
openalex   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Evaluation of finger millet genotypes for stability using parametric and non-parametric methods in India

open access: yesElectronic Journal of Plant Breeding, 2016
A study of phenotypic stability of 30 finger millet genotypes was conducted to assess genotype-environment interaction (GEI) and identify stable finger millet (Eleusine coracana (L.) Gaertn. subsp.
Salej Sood   +3 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Rank correlation between centrality metrics in complex networks: an empirical study

open access: yesOpen Physics, 2018
Centrality is widely used to measure which nodes are important in a network. In recent decades, numerous metrics have been proposed with varying computation complexity.
Shao Chengcheng   +4 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

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