Results 81 to 90 of about 332,227 (273)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Special Vinberg cones of rank 4

Journal of High Energy Physics
E.B. Vinberg developed a theory of homogeneous convex cones $$C\subset V={\mathbb{R}}^{n}$$ , which has many applications. He gave a construction of such cones in terms of non-associative rank n matrix T-algebras $$\mathcal{T}$$ , that consist of vector ...
D. V. Alekseevsky, P. Osipov
doaj   +1 more source

Matroidal Structure of Rough Sets from the Viewpoint of Graph Theory

Journal of Applied Mathematics, 2012
Constructing structures with other mathematical theories is an important research field of rough sets. As one mathematical theory on sets, matroids possess a sophisticated structure.
Jianguo Tang, Kun She, William Zhu
doaj   +1 more source

An algebraic analysis of the graph modularity

, 2014
One of the most relevant tasks in network analysis is the detection of community structures, or clustering. Most popular techniques for community detection are based on the maximization of a quality function called modularity, which in turn is based upon
Fasino, Dario, Tudisco, Francesco
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Geodesic laminations revisited

, 2006
The Bratteli diagram is an infinite graph which reflects the structure of projections in a C*-algebra. We prove that every strictly ergodic unimodular Bratteli diagram of rank 2g+m-1 gives rise to a minimal geodesic lamination with the m-component ...
A.J. Casson, E.G. Effros, Igor V. Nikolaev, M. Morse, O. Bratteli, W.A. Veech, W.A. Veech   +6 more
core   +2 more sources

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Fast Searching Strategy for Critical Cascading Paths Toward Blackouts

IEEE Access, 2018
The analysis of severe cascading blackouts is an essential issue in power grid planning and operation. As there are a tremendous number of possible cascade paths in a large power system, it is very challenging to determine the critical cascading paths ...
Zhiyuan Ma, Feng Liu, Chen Shen, Zhaojian Wang, Shengwei Mei   +4 more
doaj   +1 more source

A Probabilistic Interpretation of Sampling Theory of Graph Signals

, 2015
We give a probabilistic interpretation of sampling theory of graph signals. To do this, we first define a generative model for the data using a pairwise Gaussian random field (GRF) which depends on the graph.
Gadde, Akshay, Ortega, Antonio
core   +1 more source