Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Are interphylum spiralian relationships resolvable? [PDF]
Serra Silva A, Telford MJ.
europepmc +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
SwiftTCR: efficient computational docking protocol of TCRpMHC-I complexes using restricted rotation matrices. [PDF]
Parizi FM +10 more
europepmc +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
Concomitants of Order Statistics from a Bivariate Generalized Linear Exponential Distribution: Theory and Practice. [PDF]
Al-Zaydi AM.
europepmc +1 more source
Docking of millions: accelerating a million-scale virtual screening using deep learning. [PDF]
Ha J, Lee J, Ko J, Shin WH.
europepmc +1 more source
Prognostic Biomarker Signature of Relapse in Neuromyelitis Optica Spectrum Disorders in the CIRCLES Observational Study. [PDF]
Bach E +14 more
europepmc +1 more source
Absolute Binding Free Energy Calculations between the SARS-CoV-2 Main Protease and 130 Drug Leads Using Implicit Ligand Theory. [PDF]
Nguyen HH, Xie B, Minh DDL.
europepmc +1 more source
TransPilot: mining key transcription factors by correlating binding sites with differentially expressed genes. [PDF]
Tinghua H +7 more
europepmc +1 more source

