A minimal cellulosome‐like system in Cellulosilyticum lentocellum
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan +2 more
wiley +1 more source
What makes partnerships work? Measuring agreement in participant beliefs regarding 'core' reasons for success. [PDF]
Mathews MC, Drake AJ.
europepmc +1 more source
Cell surface CD11c as a neutrophil aging marker molecule
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source
Observability- and Identifiability-Guided Sensor-Set Design for Digital-Twin-Assisted Consolidated Bioprocessing. [PDF]
Korang Yeboah M, Asiedu NY, Addo A.
europepmc +1 more source
MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima +8 more
wiley +1 more source
DeepRank-Ab: a scoring function for antibody-antigen complexes based on geometric deep learning. [PDF]
Xu X, Coratella I, Reys V, Bonvin AM.
europepmc +1 more source
GARN3: A coarse-grained helix centered technique for RNA 3D structures prediction. [PDF]
Silva J, Cohen J, Cordeiro D.
europepmc +1 more source
HCQ-SGuA: A Plant-Growth-Inspired Hybrid Saplings Growing Up Algorithm with Quasi-Random Initialization and Chaotic Operator Control for Continuous Optimization. [PDF]
Seyyarer E.
europepmc +1 more source
A reproducible, diagnostic-guided hybrid Laplace workflow for generalized linear mixed models. [PDF]
Hamasha MM.
europepmc +1 more source
Lightweight structure-aware explanations for rule-based models: application to radiotherapy risk communication in breast cancer. [PDF]
Umbrico A +5 more
europepmc +1 more source

