Results 71 to 80 of about 173,199 (249)
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Annales Universitatis Paedagogicae Cracoviensis: Studia Mathematica, 2012 The purpose of this paper is to introduce the notion of rank function equation, and to present some results on such equations. In particular, we find all sequences $(A_{1}, ..., A_{k}, B)$ of nonzero nilpotent $n imes n$ matrices satisfying condition $$ forall, m in {1, ..., n} :, sum_{i=1}^{k} r_{A_{i}}(m) = r_{B}(m),$$ and give a ...
Marcin Skrzyński, Piotr Pokora
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Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Measuring the Accuracy Levels Regarding the Dual Business Function Criticality Classifier
IEEE Access, 2018 This paper illustrates the most recent results regarding the criticality ranking decision support classifier for an individual business function. The validated classifier is part of the business continuity points approach which estimates the recovery ...
Athanasios Podaras
doaj +1 more source
Rank functions on rooted tree quivers [PDF]
Duke Mathematical Journal, 2010 The free abelian group R(Q) on the set of indecomposable representations of a quiver Q, over a field K, has a ring structure where the multiplication is given by the tensor product. We show that if Q is a rooted tree (an oriented tree with a unique sink), then the ring $R(Q)_{red}$ is a finitely generated $\Z$-module (here $R(Q)_{red}$ is the ring R(Q)
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Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Stability Analysis of Learning Algorithms for Ontology Similarity Computation
Abstract and Applied Analysis, 2013 Ontology, as a useful tool, is widely applied in lots of areas such as social science, computer science, and medical science. Ontology concept similarity calculation is the key part of the algorithms in these applications.
Wei Gao, Tianwei Xu
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AN IMPROVED METHODOLOGY FOR MULTI-CRITERIA EVALUATIONS IN THE SHIPPING INDUSTRY
Brodogradnja, 2016 This paper presents a reliable, easy and more objective approach for ranking and determining preference in a multi-criteria decision-making problem within the shipping industry.
Daniel Osezua Aikhuele +1 more
doaj +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source