Results 91 to 100 of about 910,379 (294)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Measuring the Accuracy Levels Regarding the Dual Business Function Criticality Classifier

open access: yesIEEE Access, 2018
This paper illustrates the most recent results regarding the criticality ranking decision support classifier for an individual business function. The validated classifier is part of the business continuity points approach which estimates the recovery ...
Athanasios Podaras
doaj   +1 more source

Query Chains: Learning to Rank from Implicit Feedback

open access: yes, 2005
This paper presents a novel approach for using clickthrough data to learn ranked retrieval functions for web search results. We observe that users searching the web often perform a sequence, or chain, of queries with a similar information need.
Joachims, Thorsten, Radlinski, Filip
core   +3 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Stability Analysis of Learning Algorithms for Ontology Similarity Computation

open access: yesAbstract and Applied Analysis, 2013
Ontology, as a useful tool, is widely applied in lots of areas such as social science, computer science, and medical science. Ontology concept similarity calculation is the key part of the algorithms in these applications.
Wei Gao, Tianwei Xu
doaj   +1 more source

AN IMPROVED METHODOLOGY FOR MULTI-CRITERIA EVALUATIONS IN THE SHIPPING INDUSTRY

open access: yesBrodogradnja, 2016
This paper presents a reliable, easy and more objective approach for ranking and determining preference in a multi-criteria decision-making problem within the shipping industry.
Daniel Osezua Aikhuele   +1 more
doaj   +1 more source

College and University Ranking Systems: Global Perspectives and American Challenges [PDF]

open access: yes, 2007
Examines how higher education ranking systems function, how other countries use ranking systems, and the impact of college rankings in the United States on student access, choice, and ...
Alex Usher   +3 more
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Learning a Deep Listwise Context Model for Ranking Refinement

open access: yes, 2018
Learning to rank has been intensively studied and widely applied in information retrieval. Typically, a global ranking function is learned from a set of labeled data, which can achieve good performance on average but may be suboptimal for individual ...
Ai, Qingyao   +3 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

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