Results 71 to 80 of about 910,379 (294)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Ranking Functions

open access: yes, 2009
Ranking functions have been introduced under the name of ordinal conditional functions in Spohn (1988; 1990). They are representations of epistemic states and their dynamics. The most comprehensive and up to date presentation is Spohn (manuscript).
openaire   +2 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

A Theory for Ranking Distribution Functions [PDF]

open access: yesSSRN Electronic Journal, 2013
When is one distribution (of income, consumption, or some other economic variable) more equal or better than another? This question has proven difficult to answer in situations where distribution functions intersect and no unambiguous ranking can be attained without introducing weaker criteria than second-degree stochastic dominance.
Aaberge, Rolf   +2 more
openaire   +7 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Ranking fuzzy numbers using preference ratio: A utility function approach [PDF]

open access: yesDecision Science Letters, 2013
Ranking fuzzy numbers is one of the most important phases in any decision making process in fuzzy environments. In most cases, we deal with fuzzy numbers in the field of evaluating alternatives with fuzzy information or linguistic variables.
Soheil Sadi-Nezhad   +1 more
doaj   +1 more source

Rank and dimension functions

open access: yesThe Electronic Journal of Linear Algebra, 2015
In this paper, we invoke theory of generalized inverses and minus partial order on regular matrices over a commutative ring to define rank–function for regular matrices and dimension–function for finitely generated projective modules which are direct summands of a free module.
K. Prasad, Nupur Nandini, Divya Shenoy
openaire   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Optimal Data Collection For Informative Rankings Expose Well-Connected Graphs [PDF]

open access: yes, 2014
Given a graph where vertices represent alternatives and arcs represent pairwise comparison data, the statistical ranking problem is to find a potential function, defined on the vertices, such that the gradient of the potential function agrees with the ...
Brune, Christoph   +2 more
core   +3 more sources

Rank functions on rings

open access: yesJournal of Algebra, 1990
A (projective) rank function on a ring R is a homomorphism of pre-ordered groups, \(\rho\) : \(K_ 0(R)\to {\mathbb{R}}\), the additive group of real numbers, such that \(\rho ([R])=1\). Such a rank function exists if and only if the ring has UGN \((=\) unbounded generating number), that is, for every natural number n there is a finitely generated R ...
openaire   +2 more sources

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