Results 91 to 100 of about 478,658 (298)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

University rankings – a guide to choose a university? [PDF]

In a more and more global world, universities compete for both students and faculty staff. Do university rankings offer a good perspective when it comes to choosing a university, as a student or university professor/researcher?
Dumitru, Ionut, Jianu (Dumitru), Ionela
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Ranking de universidades chilenas: un análisis multivariado

Revista Española de Documentación Científica, 2015
En este trabajo se elabora un ranking de las universidades chilenas en base a información pública disponible. Dicho ranking toma en cuenta el carácter multivariado de estas instituciones.
Luis Firinguetti Limone, Miguel Yáñez Alvarado   +1 more
doaj   +1 more source

2014 Rankings: Key Findings Report [PDF]

, 2014
The County Health Rankings & Roadmaps program helps communities identify and implement solutions that make it easier for people to be healthy in their schools, workplaces, and neighborhoods.
Amanda Jovaag, Bridget Catlin, Julie Willems Van Dijk, Patrick Remington   +3 more
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Ranking the rankings

, 2014
In een academische wereld die steeds competitiever wordt, willen we graag weten wat ‘de beste’ universiteit is. Verschillende rankings bedienen ons op onze wenken, waaronder Times Higher Education, Sjanghai, QS en Leiden. De kritiek op die lijsten is echter niet mals, ook omdat universiteiten graag selectief shoppen in de resultaten.
Sikkema, A., van Ruitenbeek, H.C.G., Gerritsma, W., Wouters, P.   +3 more
openaire   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Implications of Academic Colonization in Brazilian Scientific Journals in Administration

RAC: Revista de Administração Contemporânea
My aim in this editorial is to reflect on the implications of colonization on Brazilian scientific journals in the field of administration. The contribution to the debate highlights how the adoption of publishing and evaluation standards from central ...
Marcelo de Souza Bispo
doaj   +1 more source

Local Knowledge When Ranking Journals: Reproductive Effects and Resistant Possibilities

Education Policy Analysis Archives, 2014
This article is based on the engagement of a US-based scholar and faculty members in a non-Western university in a mentoring exercise on publishing. It demonstrates how the “list” constructed in a particular academic department in the university for ...
Suresh Canagarajah
doaj   +1 more source