Results 81 to 90 of about 116,082 (316)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Educational ranking of a two-year degree courses in health sciences in Iranian medical universities: a strategy to identify the strengths and weaknesses

open access: yesPayesh, 2009
Objective(s): After two decades of expansion of medical universities and increasing the number of students as one of the most attainable solutions for the problem of substandard status of Iranian community health, recently, quality-based policies in ...
Aeen Mohammadi   +2 more
doaj  

The Rank of a Cograph

open access: yesThe Electronic Journal of Combinatorics, 2003
The rank of the adjacency matrix of a graph is bounded above by the number of distinct non-zero rows of that matrix. In general, the rank is lower than this number because there may be some non-trivial linear combination of the rows equal to zero. We show the somewhat surprising result that this never occurs for the class of cographs.
openaire   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

"On the Robustness of Alternative Rankings Methodologies For Australian and New Zealand Economics Departments" [PDF]

open access: yes
Just as friendly arguments based on an ignorance of facts eventually led to the creation of the definitive Guinness Book of World Records, any argument about university rankings has seemingly been a problem without a solution.
Michael McAleer   +2 more
core  

Two Phase Analysis of Ski Schools Customer Satisfaction: Multivariate Ranking and Cub Models

open access: yesStatistica, 2014
Monitoring tourists' opinions is an important issue also for companies providing sport services. The aim of this paper was to apply CUB models and nonparametric permutation methods to a large customer satisfaction survey performed in 2011 in the ski ...
Rosa Arboretti   +2 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Rankings games [PDF]

open access: yes
Research rankings based on publications and citations today dominate governance of academia. Yet they have unintended side effects on individual scholars and academic institutions and can be counterproductive. They induce a substitution of the “taste for
Margit Osterloh, Bruno S. Frey
core  

Striving for excellence in the age of rankings: Insights from two leading research universities in Latin America

open access: yes, 2021
© Ellen Hazelkorn and Georgiana Mihut 2021.The higher education sector’s main challenges in Latin America can be addressed with guidance from the few flagship universities of the region.
Bernasconi Ramírez, Andrés, Knobel M.
core   +1 more source

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