Results 111 to 120 of about 116,766 (290)

Recommendations for Future Efforts in RANS Modeling and Simulation [PDF]

open access: yes
The roadmap laid out in the CFD Vision 2030 document suggests that a decision to move away from RANS research needs to be made in the current timeframe (around 2020).
Bush, Robert H.   +5 more
core   +1 more source

AI-RAN: Transforming RAN with AI-Driven Computing Infrastructure

open access: yesIEEE Communications Magazine
The radio access network (RAN) landscape is undergoing a transformative shift from traditional, communication-centric infrastructures towards converged compute-communication platforms. This article introduces AI-RAN which integrates both RAN and artificial intelligence (AI) workloads on the same infrastructure.
Kundu, Lopamudra   +4 more
openaire   +2 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

A numerical study on the effects of high-lift devices on the aerodynamic characteristics of a large aircraft

open access: yesHangkong gongcheng jinzhan
The high-lift device of an aircraft can improve its lift and safety, and the reasonable application of the high-lift device is crucial to improving the safety of the aircraft.
ZHU Guowang   +3 more
doaj   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Topological optimization of the axial compressor blade of aircraft gas turbine engine

open access: yesАвіаційно-космічна техніка та технологія
The requirements for the efficiency, reliability, and environmental friendliness of technical systems in modern mechanical engineering are constantly increasing.
Maryna Pikul   +3 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

Etude numérique de l’écoulement autour de l’éolienne NORDEX N80

open access: yesRevue des Énergies Renouvelables, 2013
Une étude basée sur la résolution des équations moyennées de Navier-Stockes (RANS) écrites pour un écoulement bidimensionnel axisymétrique en régime stationnaire a été effectuée à l’aide du code saturne d’EDF pour caractériser l’écoulement autour d’une ...
M. Tata, A. Smaïli, O. Guerri
doaj  

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