Results 111 to 120 of about 136,501 (295)

A numerical study on the effects of high-lift devices on the aerodynamic characteristics of a large aircraft

Hangkong gongcheng jinzhan
The high-lift device of an aircraft can improve its lift and safety, and the reasonable application of the high-lift device is crucial to improving the safety of the aircraft.
ZHU Guowang, WU Hengbin, HUANG Shenghong, NI Zao   +3 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Topological optimization of the axial compressor blade of aircraft gas turbine engine

Авіаційно-космічна техніка та технологія
The requirements for the efficiency, reliability, and environmental friendliness of technical systems in modern mechanical engineering are constantly increasing.
Maryna Pikul, Kateryna Balalaieva, Anton Balalaiev, Andrii Melchenko   +3 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

HURP Is a Ran-Importin β-Regulated Protein that Stabilizes Kinetochore Microtubules in the Vicinity of Chromosomes [PDF]

, 2006
Herman H.W. Silljé, Susanna Nagel, Roman Körner, Erich A. Nigg   +3 more
openalex   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Etude numérique de l’écoulement autour de l’éolienne NORDEX N80

Revue des Énergies Renouvelables, 2013
Une étude basée sur la résolution des équations moyennées de Navier-Stockes (RANS) écrites pour un écoulement bidimensionnel axisymétrique en régime stationnaire a été effectuée à l’aide du code saturne d’EDF pour caractériser l’écoulement autour d’une ...
M. Tata, A. Smaïli, O. Guerri
doaj  

RANS-based fast computational methods for indoor flows: a framework-driven performance assessment for a simple benchmark

Developments in the Built Environment
Reliable indoor climate prediction requires reliable tools. Complex airflow predictions often involve the use of physical or numerical models. Computational fluid dynamics (CFD) is a popular, high-fidelity method that can produce reliable predictions ...
Eugene Mamulova, Marcel Loomans, Twan van Hooff   +2 more
doaj   +1 more source

FCC2002.127.ran

, 2020
Robyn Fiori
openalex   +1 more source

Early retinal neurodegeneration and impaired Ran-mediated nuclear import of TDP-43 in progranulin-deficient FTLD [PDF]

, 2014
Michael E. Ward, Alice Taubes, Robert Y. Chen, Bruce L. Miller, Chantelle F. Sephton, Jeffrey M. Gelfand, Sakura Minami, John Boscardin, Lauren Herl Martens, William W. Seeley, Gang Yu, Joachim Herz, Anthony J. Filiano, Andrew E. Arrant, Erik D. Roberson, Timothy W. Kraft, Robert V. Farese, Ari Green, Li Gan   +18 more
openalex   +1 more source