Results 31 to 40 of about 44,386 (235)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Characterization of Asphalt Mixtures Produced with Coarse and Fine Recycled Asphalt Particles

open access: yesInfrastructures, 2019
Utilizing recycled asphalt pavements (RAP) in pavement construction is known as a sustainable approach with significant economic and environmental benefits.
S. Saeed Saliani   +3 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Experimental Investigation on Rheological Properties of Recycled Asphalt Pavement Mastics

open access: yesApplied Rheology, 2015
Studies have shown that rheology of asphalt mastic plays an important role in pavement performance, specifically for the case of recycled asphalt pavement (RAP) mastics which contains mostly aged binder.
Mannan Umme Amina   +3 more
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

HIGHER SCHOOL AND EMPLOYER ARE BUSINESS-EDUCATION PARTNERS

open access: yesМодернизация, инновация, развитие, 2016
The competence approach in education means to focus on developing learning capabilities, self-determination, socialization and development of personality.
V. A. Pokhvoshchev   +2 more
doaj  

Linguistic and Extralinguistic Aspects of Study of Modern Russian Rap Texts

open access: yesНаучный диалог, 2021
An overview of modern domestic and foreign linguistic studies of rap texts is presented. The features of rap as part of the global hip-hop culture are considered.
E. V. Grudeva, A. A. Diveeva
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

DEVELOPMENT OF METHODS FOR STATE MANAGEMENT OF INVESTMENT PROCESSES, INVESTMENT OF RESOURCES

open access: yesМодернизация, инновация, развитие, 2016
Owing to the accessibility to funds and resources required to support economics on the whole and most important branches in particular, the state is main investor to real sector of Russian economics. Unfortunately, this investment activity is implemented
A. Yu. Semenikhin
doaj  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy