Immunomodulatory properties of quercetin-3-O-α-L-rhamnopyranoside from Rapanea melanophloeos against influenza a virus. [PDF]
Influenza infection is a major public health threat. The role of influenza A virus-induced inflammatory response in severe cases of this disease is widely recognized. Drug resistance and side effects of chemical treatments have been observed, resulting in increased interest in alternative use of herbal medications for prophylaxis against this infection.
Mehrbod P +7 more
europepmc +10 more sources
Experimental validation and computational modeling of anti-influenza effects of quercetin-3-O-α-L-rhamnopyranoside from indigenous south African medicinal plant Rapanea melanophloeos. [PDF]
Abstract Background Influenza A virus (IAV) is still a major health threat. The clinical manifestations of this infection are related to immune dysregulation, which causes morbidity and mortality. The usage of traditional medication with immunomodulatory properties against influenza infection has been increased recently.
Mehrbod P +6 more
europepmc +9 more sources
A 56-Day Oral Toxicity Study of the Aqueous Extract of Rapanea melanophloeos (L.) Mez in Rats. [PDF]
Rapanea melanophloeos is a tropical tree that is extensively utilized in African traditional medicine to treat helminthiases, tuberculosis, and heart‐water. As with many other medicinal plants, there is insufficient information regarding the safety of therapeutic R. melanophloeos extracts. An aqueous extract of R.
Amenya HZ +4 more
europepmc +6 more sources
Potential implications of the use of Rapanea melanophloeos (L.) Mez against mycobacteria
Abstract Tuberculosis (TB) is a threat to a large population across the globe. Rapanea melanophloeos (L.) Mez, commonly known as the Cape beech, is a plant that is traditionally used in the treatment of tuberculosis and TB-related symptoms. The aim of this study, was to evaluate the pharmacological effects of a leaf ethanolic extract (1:10, w:v) of R.
Lydia Gibango +2 more
exaly +5 more sources
Harvesting of products from plants in the wild is widespread throughout southern Africa. Particularly important products are plant parts used in traditional medicine. However, the impacts of harvesting practices are rarely quantified, with as yet insufficient generic rules across species and life forms. This limits the predictive ability to monitor and
J. Botha +2 more
doaj +5 more sources
Wounds on Rapanea melanophloeos provide habitat for a large diversity of Ophiostomatales including four new species [PDF]
Rapanea melanophloeos, an important canopy tree in Afromontane forests, is commonly utilised for medicinal bark harvesting. Wounds created from these activities provide entrance for many fungi, including arthropod-associated members of the Ophiostomatales and Microascales (ophiostomatoid fungi).
Tendai Musvuugwa +5 more
exaly +7 more sources
Abstract Rapanea melanophloeos is a tree indigenous to Southern Africa. Previous work has reported on the potential of the bark and leaf extracts/decoctions as antifungal, anthelmintic and molluscicidal treatments. This study characterised the antidiabetic potential of R.
N. Lotter +5 more
exaly +4 more sources
Myrsine africana L. and Rapanea melanophloeos L. belong to the plant family Myrsinaceae. Various rural communities in Kenya, such as smallholder farmers and pastoralists, use them to treat their livestock. The anthelmintic effects/activities of leaves and fruits of M. africana and fruits of R.
J.B. Githiori +3 more
exaly +6 more sources
South Africa's Best BARK Medicines Prescribed at the Johannesburg Muthi Markets for Skin, Gut, and Lung Infections: MIC's and Brine Shrimp Lethality. [PDF]
Indigenous trade of medicinal plants in South Africa is a multi-million-rand industry and is still highly relevant in terms of primary health care.
Khumalo GP +3 more
europepmc +2 more sources

