Results 191 to 200 of about 27,135,528 (306)

Rapid Analysis of NAD and Other Phosphorylated Metabolites in Complex Biological Samples by Hydrophilic Interaction Liquid Chromatography Coupled with Tandem Mass Spectrometry. [PDF]

Anal Chem
Pravdova A, Kleinert M, Henderson J, Kafkia E, Pladevall-Morera D, Yonamine CY, Treebak JT, Brodiazhenko T, Terenin I, Zylicz JJ, Moritz T, Hodek O.   +11 more
europepmc   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

Molecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both, Ingrid A. M. Derks, Raphaël Vanleyssem, Marine Leclercq, Najla El Hachem, Pierre Close, Eric Eldering, Marco Vincent Haselager   +7 more
wiley   +1 more source

LAM-CAM: <i>In Vivo</i> Model for Rapid Analysis of Lymphangioleiomyomatosis Tumor Formation and Inhibition. [PDF]

Am J Respir Cell Mol Biol
Kundu N, Belcher A, Di Martino JS, Holz MK.   +3 more
europepmc   +1 more source

A novel Fiji/ImageJ plugin for the rapid analysis of blebbing cells. [PDF]

PLoS One, 2022
Vosatka KW, Lavenus SB, Logue JS.
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Rapid Analysis of the Chemical Composition of Xiaoban Kangfu Capsules Based on UHPLC-Q-Exactive Orbitrap MS/MS Combined with Molecular Networks. [PDF]

Pharmaceuticals (Basel)
Luo X, Liao Y, Qing T, Zhao J, Cai W.
europepmc   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Flow cytometry for rapid analysis of bacteriostatic versus bactericidal effects in Legionella pneumophila disinfection. [PDF]

Anal Bioanal Chem
Liang Y, Heining L, Elsner M, Seidel M.
europepmc   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Rapid Analysis of DEER Signals Including Short Distances. [PDF]

J Phys Chem Lett
Sinha Roy A, Assafa TE, Dzikovski B, Joshi N, Freed JH.   +4 more
europepmc   +1 more source