Results 171 to 180 of about 27,135,528 (306)

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Chemometrics-assisted spectroscopic methods for rapid analysis of combined anti-malarial tablets. [PDF]

open access: yesJ Food Drug Anal, 2023
Pruksapha P   +5 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Implementing a rapid analysis framework to evaluate wellness initiatives in Massachusetts federally qualified health centers. [PDF]

open access: yesBMC Health Serv Res
Miranda I   +10 more
europepmc   +1 more source

A Rapid Analysis of Pyrite

open access: yesNIPPON KAGAKU KAISHI, 1942
Kazuo INOUE   +2 more
openaire   +2 more sources

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

CRUSTY: a versatile web platform for the rapid analysis and visualization of high-dimensional flow cytometry data. [PDF]

open access: yesNat Commun, 2023
Puccio S   +9 more
europepmc   +1 more source

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