Results 151 to 160 of about 2,823,635 (315)
Surface proteomics on nanoparticles, a step to simplify the rapid prototyping of nanoparticles
, 2017 Engineered nanoparticles for biomedical applications requireincreasing effectiveness in targeting specific cells while preservingnon-target cell’s safety.
Bayat, Narges, +6 more
core +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Rapid assessments in urban areas [PDF]
The diversity of urban areas presents substantial challenges to the validity of information from rapid assessments, yet CARE's experiences in Bangladesh and Tanzania suggest a number of ways that rapid assessment procedures can be strengthened to address
Garrett, James L., Downen, Jeanne
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Program for Integration and Rapid Analysis of Mass Isotopomer Distributions (PIRAMID). [PDF]
Bioinformatics, 2023 Gomez JD +7 more
europepmc +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Evaluation of a notes-based rapid qualitative analysis method to facilitate implementation
Implementation Science CommunicationsBackground Qualitative methodologies offer a nuanced approach to understanding stakeholder perspectives, preferences, and context in implementation research.
Rachel Brown +4 more
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Advanced ScienceForensic case samples collected in sexual assaults typically contain DNA from multiple sources, which complicates short‐tandem repeat (STR) profiling. These samples are typically sent to a laboratory to separate the DNA from sperm and non‐sperm sources ...
Mohamed Elsayed +12 more
doaj +1 more source
Mapping the Navy Innovation Network Using Social Network Analysis [PDF]
, 2018 Defense Analysis PosterThis research sought answers to the following the questions: A - What are the key nodes and networks in the Navy Innovation Network? B - What are the ties that link together members of the informal network?
Warren, Camber +2 more
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