Results 261 to 270 of about 2,823,635 (315)

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Correction to: wTSA-CRAFT: an open-access web server for rapid analysis of thermal shift assay experiments. [PDF]

Bioinform Adv
europepmc   +1 more source

Establishment of a multiplex PCR-CE assay for the simultaneous and rapid analysis of age markers for Calliphora vicina pupae. [PDF]

Int J Legal Med
Hartmann K, Bamberg M, Seum S, Amendt J, Verhoff MA, Zehner R.   +5 more
europepmc   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Rapid Analysis of Compounds from Piperis Herba and Piperis Kadsurae Caulis and Their Differences Using High-Resolution Liquid-Mass Spectrometry and Molecular Network Binding Antioxidant Activity. [PDF]

Molecules
Shi D, Shi D, Liao N, Liu H, Gao W, Zhong S, Zheng C, Chen H, Xiao L, Zhu Y, Huang S, Zhang Y, Hu Y, Zheng Y, Ji J, Cheng J.   +15 more
europepmc   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

RAPID SPECTROMETER ANALYSIS

, 1968
openaire   +1 more source

Link Rapid I/O Transceiver-NIU Signal Integrity Analysis & Measurements

, 2007
E. Di Michele, G. Olivieri, L. Giovannucci, ORLANDI, Antonio   +3 more
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"Rapidized" cognitive task analysis

IEEE Intelligent Systems, 2012
Cognitive task analysis is the study of macrocognitive work and the modeling of the knowledge and reasoning of domain experts, which inform the creation of intelligent systems. Over the past quarter-century, most research on decision-making and other aspects of macrocognition has been conducted using some form of cognitive task analysis. In this essay,
Wayne Zachary, Robert R. Hoffman, Beth Crandall, Tom Miller, Christopher P. Nemeth   +4 more
openaire   +1 more source