Results 131 to 140 of about 488,982 (265)

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Development of a broad-lineage Lassa virus rapid diagnostic test informed by the WHO REASSURED framework. [PDF]

J Clin Microbiol
Shin H, Lee M, Choi M-M, Kim J-W, Yi H, Whitmer S, Sayyad L, Montgomery J, Klena J, Chung Y-S.   +9 more
europepmc   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Accuracy of recording of malaria rapid diagnostic test results in Uganda. [PDF]

Malar J
Ssewante N, Namuganga JF, Katahoire A, Musoke J, Mutesi N, Humes M, Griffith K, Aponte JJ, Soebiyanto R, Cooper S, Agaba B, Opigo J, Lindblade KA, Mpimbaza A.   +13 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Evaluation of recombinant Taenia multiceps HSP70 antigen in a dipstick-based rapid diagnostic test for ovine coenurosis. [PDF]

BMC Vet Res
Gunyakti-Kilinc S, Celik F, Kesik HK, Uslug M, Simsek S.   +4 more
europepmc   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Characterization of arbovirus infections in patients within Haiti by screening discarded malaria rapid diagnostic test cassettes. [PDF]

PLoS Negl Trop Dis
Matulis GA, Smith HP, Hall G, Katich RS, Delp KL, Douglas CE, Williams J, Hirsch S, Kumar R, Pshea-Smith I, Lilak AA, Okech BA, Ricks K, Stefan CP, Existe A, Kugelman JR, Sutherland I, Dunford J, Boncy J, von Fricken ME, Koehler JW.   +20 more
europepmc   +1 more source

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall, Kimberly Kwei, Rolando J. Acosta, Bharatkumar Koyani, Erin Robertson, Pratyush Rai, Roland Barge, Emily Timm, Nicollette L. Purcell, Natasha Desai, Dhanesh Patel, Ana‐Maria Visoiu‐Knapp, Samuel Stuart, Rinol Alaj, Matthew F. Wipperman, Oren Levy, Joan A. O'Keefe   +16 more
wiley   +1 more source

Investigating the Abbott-Bioline™ malaria antigen Pf/Pv rapid diagnostic test. [PDF]

Malar J
Aung MTT, Thu AM, Phyo AP, Aung WL, Pateekhum C, Proux S, Yotyingaphiram W, Archusuksan L, Wongaeka M, White NJ, Day NP, Nosten F.   +11 more
europepmc   +1 more source